Practices participating in a dental PBRN have substantial and advantageous diversity even though as a group they have much in common with dentists at large
© Makhija et al; licensee BioMed Central Ltd. 2009
Received: 22 May 2009
Accepted: 15 October 2009
Published: 15 October 2009
Practice-based research networks offer important opportunities to move recent advances into routine clinical practice. If their findings are not only generalizable to dental practices at large, but can also elucidate how practice characteristics are related to treatment outcome, their importance is even further elevated. Our objective was to determine whether we met a key objective for The Dental Practice-Based Research Network (DPBRN): to recruit a diverse range of practitioner-investigators interested in doing DPBRN studies.
DPBRN participants completed an enrollment questionnaire about their practices and themselves. To date, more than 1100 practitioners from the five participating regions have completed the questionnaire. The regions consist of: Alabama/Mississippi, Florida/Georgia, Minnesota, Permanente Dental Associates, and Scandinavia (Denmark, Norway, and Sweden). We tested the hypothesis that there are statistically significant differences in key characteristics among DPBRN practices, based on responses from dentists who participated in DPBRN's first network-wide study (n = 546).
There were statistically significant, substantive regional differences among DPBRN-participating dentists, their practices, and their patient populations.
Although as a group, participants have much in common with practices at large; their substantial diversity offers important advantages, such as being able to evaluate how practice differences may affect treatment outcomes, while simultaneously offering generalizability to dentists at large. This should help foster knowledge transfer in both the research-to-practice and practice-to-research directions.
Practice-based research networks (PBRNs) have been in existence in the United States since the 1970s . The purpose of these networks is to join practitioners with academic researchers in developing and answering relevant research questions that can directly impact daily clinical practice . PBRNs offer unique advantages both to research and quality improvement, and foster information sharing between practitioners [3–6].
Traditionally, clinical research projects have been conducted in academic settings. However, less than 1% of Americans receive their health care in that type of setting . With studies initiated and developed by non-academic practitioners and conducted in their offices, results should be more relevant to these clinicians. Therefore, these studies should lead to improved clinical treatment in a shorter amount of time in these non-academic settings, as compared to conventional clinical research done in academic settings by academic dentists [6, 8, 9].
In the past, PBRNs have focused on non-dental areas, such as family medicine, internal medicine, pediatrics, and ophthalmology. Recognizing the success of physician-based PBRNs, the U.S. National Institute of Dental and Craniofacial Research (NIDCR) funded three oral health PBRNs in 2005, one of which is "DPBRN" (Dental Practice-Based Research Network). The purpose of these networks is to answer questions raised by dental practitioners in everyday clinical practice and to evaluate the effectiveness of current strategies to prevent, manage, and treat oral diseases and conditions [8, 9]. DPBRN is unique in that it encompasses four regions in the United States and one in Scandinavia. The United States regions are: (1) the Alabama/Mississippi region (AL/MS), which almost entirely comprises dentists in private practice, although a few practices are in public health settings; (2) the Florida/Georgia region (FL/GA), which also comprises almost entirely dentists in private practice, although a few practices are in public health settings; (3) the Minnesota region (MN), which mainly comprises dentists employed by HealthPartners (HP), but which also has dentists in private practice in Minnesota; (4) the Permanente Dental Associates region (PDA), which is comprised entirely of dentists in Oregon and Washington in the PDA organization, in cooperation with the Kaiser Permanente Northwest (KPNW) Research Foundation's Center for Health Research; and (5) the Scandinavian (SK) region comprises dentists in Denmark, Norway, and Sweden, about one-half of whom are in private practice and one-half of whom are in a public health setting .
The regions comprising DPBRN were selected for various reasons and have been described previously . The University of Alabama at Birmingham (UAB) is the administrative base for DPBRN and previously worked with Florida and Georgia . The University of Florida conducted restorative dentistry practice-based studies in the past in Florida as well as Scandinavia [11, 12]. Including Scandinavia in DPBRN adds to practitioner diversity within the network and helps to identify both preventive and restorative international variations in treatment, which can help identify research priorities for future DPBRN projects [6, 13]. For two DPBRN regions, collaborations were established with two organizations: HP of Minneapolis, Minnesota, and PDA, of the greater metropolitan Portland, Oregon area. HP is a prepaid, multi-specialty group that provides comprehensive health care. The HP Dental Group is staffed by 58 dentists at 14 clinic locations that serve about 100,000 enrollees. PDA is a multi-specialty dental group that contracts with KPNW to provide dental services for KPNW prepaid comprehensive health plan members. PDA includes 117 dentists in 14 dental clinics in Oregon and Washington that serve about 180,000 members with dental benefits. The HP and PDA groups have conducted practice-based research, including joint collaborative projects [14, 15].
In order to participate in DPBRN, practitioners must complete a DPBRN Enrollment Questionnaire. Dental practices are recruited in several ways. Licensed practitioners from the regions (AL/MS, FL/GA, MN, PDA, and SK) receive a mailing that describes DPBRN and invites them to participate. They are also recruited through DPBRN booths at dental meetings, at DPBRN orientation sessions, lectures given to dental students, as well as the public DPBRN website .
Recent findings from the DPBRN Enrollment Questionnaire are consistent with the conclusion that the DPBRN practitioner-investigators have much in common with dentists at large , meaning that results from DPBRN studies should be generalizable to the larger population of dentists. Although one objective of DPBRN is to comprise practices from which results should be generalizable to practices at large, another equally-important objective is that these practices also constitute a diverse range of practitioner-investigators, practice settings, patient populations, and geographic locations. This diverse range of practice settings should contain practices in private practice, public health practice, and preferred provider, managed care, or health maintenance organization settings.
Meeting the objective for geographic diversity not only requires practices from different regions nationally and globally, but also requires a mix of rural and urban locations. Therefore, although our earlier work documented that DPBRN practitioner-investigators have much in common with dentists at large , the objective of this current paper is to determine whether or not we met another DPBRN objective: to comprise a diverse range of practice settings and practitioners. Having substantial diversity offers important advantages, such as being able to evaluate how practice differences may affect treatment outcomes. We determined whether or not we met this objective by testing the hypothesis that there are statistically significant and substantive differences in key characteristics across DPBRN regions, based on responses to the DPBRN Enrollment Questionnaire from dentists who participated in DPBRN's first network-wide study.
The DPBRN Enrollment Questionnaire
Number of Dentists Participating in the Enrollment and Caries Questionnaires
Number of Dentists Who Completed a DPBRN Enrollment Questionnaire, by Region
Number of Dentists Who Completed a DPBRN Enrollment Questionnaire and Who Also Completed the DPBRN Caries Questionnaire, by Region (restricted to practitioners who perform at least some restorative dentistry procedures)
Practitioner and Practice Characteristics Available From the DPBRN Enrollment Questionnaire
Dental procedure characteristics
Dentist individual characteristics
Number of different sites at which you provide patient care at least once each week
Percentage of your time each day spent doing specific types of procedures 3
Whether you practice full-time or part-time
Percentage of procedures that are done mainly for esthetic reasons
Number of full-time dental hygienists in your practice
Percentage of revenues or charges that are derived from different payment sources 2
Percentage of certain procedures that you refer to other dentists 4
Year of graduation from dental school
Number of full-time dental assistants in your practice
Percentage of patients who get certain services at some time while they are patients in your practice 5
Number of dental chairs you use regularly in your part of the practice
Number of root canal procedures that you do or refer each month
Number of patient visits you personally have during a typical week
Number of dental extractions that you do or refer each month
Typical number of days a patient has to wait for a new patient examination
Typical number of days a patient has to wait for a treatment procedure appointment
Practice busyness 1
The DPBRN Caries Questionnaire
The first network-wide study involving all five regions in DPBRN was entitled the "Assessment of Caries Diagnosis and Caries Treatment Questionnaire". This 10-page "Caries Questionnaire" inquired about which caries diagnostic and treatment procedures practitioner-investigators use, and how commonly they use them in their practices. Additionally, it posed certain clinical scenarios and respondents answered how they would recommend treating hypothetical patients in those scenarios.
A preliminary version of the questionnaire was administered to 16 DPBRN dentists to assess feasibility and comprehension of each questionnaire item. A subsequent pilot study finalized documentation of comprehension and item test-retest reliability across 15 days using a sample of 35 network dentists. All items in the final version met a test-retest reliability cutoff of kappa > 0.7.
To be eligible to complete the Caries Questionnaire, the practitioner-investigator must be a general dentist, pediatric dentist, or do at least some restorative dentistry, as well as have completed the DPBRN Enrollment Questionnaire. The questionnaires were mailed to the eligible practitioners, with second and third mailings sent to non-responders. One of the objectives of this study was to receive 200 responses to meet sample size requirements. Of the 970 DPBRN enrollees who were eligible, 546 completed the Caries Questionnaire, which well-exceeded expectations. Table 1 provides the distribution of participants who completed the Caries Questionnaire, by region.
The protocol was approved by the UAB, University of Florida, HP, PDA, and Scandinavian Institutional Review Boards and informed consent was explained and ascertained from each practitioner.
To test the hypothesis that there are statistically significant differences across DPBRN regions with regard to dentist and practice characteristics, we used responses to the Enrollment Questionnaire made by practitioner-investigators who participated in the Caries Questionnaire. Analytic datasets were extracted, underwent a final quality-control analysis and were converted to SAS® (SAS Institute, Cary, NC) and SPSS® 12.0 (SPSS, Inc, Chicago, IL) datasets. For categorical responses, chi-square goodness-of fit tests were used to test for differences between practitioners who completed the Enrollment Questionnaire and the Caries Questionnaire. Two-sample t-tests were used to examine continuous responses. For all cases, significance was determined by p < 0.05. Because some DPBRN responses were categorized into percentile ranges, a midpoint was assigned to each range in order to derive an approximate mean and standard deviation for reporting. We used this method for the variables regarding number of dental chairs, number of patients/week, number of days waiting for a new patient exam, and typical number of days a patient has to wait for a treatment procedure appointment. All analyses were done using SPSS® 12.0 and were independently verified using SAS® 9.1.
[Additional file 1-Table S1] presents the results comparing DPBRN practitioners who completed the Caries Questionnaire, by region.
The number of different sites at which the practitioner provides care varied among the regions, with the MN and SK regions having the highest percentage of practitioners working at more than one location. These two regions also had the highest percentage of practitioners who do not practice full-time (19% and 30% respectively).
The number of full-time hygienists in the practice varied greatly across the regions. FL/GA (63%) and SK (72%) practices most commonly reported one full-time dental hygienist. MN and PDA practices had the highest percentage of three or more hygienists, due to the group practice structure in the PDA and HP practices.
The MN and SK practices had the highest percentages for having more than three full-time dental assistants, and the FL/GA practices had the highest mean number of dental chairs used regularly in their practices. Regarding the number of patient visits during a typical week, the AL/MS, FL/GA, and PDA practices most commonly reported 21-40 visits per week, while the MN and SK practices most commonly reported 41-60 visits per week. PDA practices reported the highest mean number of days that a patient has to wait for a new patient examination and a treatment procedure (29 days and 27 days; respectively). A high percentage of practitioner-investigators in all regions answered that they were able to provide care to all their patients, and were not overburdened.
The Enrollment Questionnaire divided patient ages into four groups: 1-18, 19-44, 45-64, and 65 years or older. Practitioner-investigators in all five regions most commonly reported that between 1% and 20% of their patients were between the ages of 1-18. For patients aged 19-44 and 45-64 years, practitioner-investigators from all regions most commonly reported that patients in this age group comprised between 21% and 40% of their patients. For all regions, most practitioners answered that patients aged 65 or older comprised 20% of their patients or less.
With regard to race of the patients, practitioner-investigators in the AL/MS, FL/GA, and PDA regions most commonly reported that 61-80% of their patients were white. MN and SK practitioner-investigators most commonly reported that between 81% and 100% of their patients were white. Practitioner-investigators in all regions most commonly reported that Black/African American patients comprised 20% of their patients or less.
With respect to payment sources, most of the SK practitioner-investigators reported that insurance comprises 20% or less of their practice's revenue; AL/MS and FL/GA practitioner-investigators most commonly reported that the figure was between 41% and 60% of their practice's revenue. MN and PDA practitioner-investigators most commonly reported that insurance comprised between 81% and 100% of their practice's revenue. In the self-pay category, MN and PDA practitioner-investigators most commonly reported that practice revenue coming from self-pay was 20% or less, which is because most of these practitioner-investigators practice in a HMO setting.
Dental procedure characteristics
Although the Caries Questionnaire was limited to those who perform at least some restorative dentistry procedures, the amount of time devoted to performing non-implant restorative work nonetheless varied significantly across the regions. Practitioner-investigators in the MN region reported the highest percentage of time devoted to non-implant restorative procedures.
Most DPBRN practitioner-investigators spend 20% or less of their time placing or restoring implants, with a large percentage in the PDA region (77%) reporting that they do no implant procedures. There also were statistically significant differences between DPBRN regions and their practitioner-investigators with regard to the percentage of time they spend performing dental extractions, periodontal therapy, endodontic therapy, other procedures, and procedures done mainly for esthetic reasons [Additional file 1-Table S1].
With regard to referrals, practitioner-investigators in all DPBRN regions overwhelmingly responded that they refer between 81% and 100% of implant surgery, although practitioner-investigators in the SK region reported a significantly lower percentage. Practices in the AL/MS, FL/GA, and SK regions refer significantly lower percentages of their implant restorations, compared to practitioner-investigators in the MN and PDA regions. The PDA organization currently refers all implant restorations to dentists in their communities [Additional file 1-Table S1].
Although there were statistically significant differences between DPBRN regions, most practitioner-investigators refer 20% or less of their patients who need anterior root canal procedures. Referring molar root canal procedures is common among practitioner-investigators in the AL/MS, FL/GA, and PDA regions, but much less so among practitioner-investigators in the MN and SK regions. There were statistically significant differences between DPBRN regions with regard to the percentage of patients who are referred for non-surgical extractions [Additional file 1-Table S1].
Practitioners were asked questions regarding the percentage of their patients who receive certain services at some time while they are patients in their practice. There was substantial and statistically significant diversity across DPBRN practices. For example, when asked about diet counseling and blood pressure screening, the AL/MS, FL/GA, and SK practitioner-investigators responded that 20% or less of their patients receive this service, whereas these services were much more commonly provided in MN and PDA practices. Oral cancer screening and oral hygiene instruction services were very common in DPBRN practices, although even on these services, there was significant diversity among practices. Patient education from pamphlets was common, although again, there was significant diversity among DPBRN practices [Additional file 1-Table S1].
The use of intraoral photographs and video images was not common, although there was statistically significant and substantive diversity evident. Significant diversity was also evident with regard to the percentage of patients who are provided at-home tooth whitening.
The monthly practice volume of root canals and dental extractions - regardless of whether the DPBRN practitioner-investigator performed the procedure or whether it was referred to another dentist - also showed statistically significant and substantive diversity among DPBRN practices [Additional file 1-Table S1].
Dentist individual characteristics
Most DPBRN practitioner-investigators are male, although there is significant diversity in this percentage across DPBRN regions. With regard to race of the practitioner-investigator, 100% of those in the Scandinavian region are white, in contrast to the other regions, which ranged from 80% to 94%. Practitioner-investigators of Asian descent comprise 14% of dentists in the PDA region.
There is substantial diversity within each DPBRN region as well as across regions with regard to the year in which the practitioner-investigator graduated from dental school. PDA has the youngest practitioner-investigators, with a plurality having graduated since 1994 [Additional file 1-Table S1].
Not shown in [Additional file 1-Table S1], DPBRN practitioner-investigators graduated from a broad range of dental schools. These include: University of Copenhagen, Denmark, Emory University, Georgetown University, Northwestern University, Oregon Health and Science University, School of Dentistry Malmö, Sweden, Tufts University, University of Alabama at Birmingham, University of Florida, University of Iowa, University of Michigan, University of Minnesota, University of Washington, and University of Oslo, Norway. This diverse group of dental schools, the full list of which includes many more dental schools, shows the wide range of didactic instruction that DPBRN practitioner-investigators have had.
In our previous DPBRN paper , we concluded that DPBRN practitioner-investigators as a group had much in common with dentists at large. The results in this current paper take the next analytic step and indicate that practitioner-investigators participating in DPBRN vary substantially with regard to many characteristics, including practice setting, patient population, dental procedure characteristics, and dentist individual characteristics. Previous research has shown that dental practice characteristics are related to the diagnostic services , preventive procedures , and treatment procedures [20, 21] that patients receive, as well as to their treatment outcomes . Establishing a PBRN with a diverse range of these practice characteristics creates a research context ripe for relating these characteristics to treatment outcomes and to success in moving new knowledge into routine practice.
Having a diverse group of individuals in DPBRN is important in that research topics come from members. Details regarding this process are provided elsewhere . DPBRN receives input from members of the network at each step of the process. These ideas come from suggestions to our website http://www.DentalPBRN.org, face-to-face meetings, orientation sessions, or visits to the practice during other studies. The ideas are then sent to the Executive Committee (EC), which has at least one practitioner-investigator representative from each region. Ideas for studies are discussed and prioritized by the EC, and if approved, are sent to the NIDCR to determine whether it overlaps with studies already funded by them. If not, DPBRN forms a protocol working group which includes at least one practitioner-investigator member. The idea is then formed into a full grant application, with the DPBRN practitioner-investigator member providing input to ensure that the study will be feasible and practical to conduct in a typical clinical practice.
Past studies have shown that it takes an average of 17 years to turn just 14% of original research findings into changes in care that will benefit patients . When research is done in an academic setting, patients are not typically representative of the majority of those who receive care in a private setting, and the results of these studies may not be applicable to many communities [23–25]. PBRNs have great potential to speed this process [23, 24, 26–29]. If practitioners are involved with the development of the studies and are involved in projects that are relevant to everyday clinical practice (which is what DPBRN does), they are more likely to use the results . An assessment of how applicable the findings of PBRN research are to the dental community at large is important in evaluating its impact on changing clinical practice . With regard to DPBRN specifically, because ideas for almost all studies conducted by DPBRN originate from DPBRN practitioner-investigators themselves, DPBRN results have the potential to help shorten the delay before study results are incorporated into clinical practice . In a 2000 ADA Membership Needs and Opinion Survey, 80% of ADA members felt that implementing treatment for their patients based on scientific findings was a 'critical' or 'significant' issue, stressing the importance of the findings from PBRNs .
These results do have some limitations. Of the 970 practitioners who received the Caries Questionnaire, 546 returned a completed questionnaire. Additionally, the majority of DPBRN practitioners who completed an Enrollment Questionnaire and the Caries Questionnaire were from the AL/MS region; 73.1% and 56.0% respectively. Although the necessary sample sizes for both questionnaires far exceeded a priori requirements, having a large number of respondents from one region also meant that this region necessarily contributed a higher percentage of respondents network-wide. DPBRN dentists, while coming from a diverse range of geographical areas and practice types, are not selected randomly. Similarly, those dentists who elected to participate in the first network-wide study are self-selected and therefore not random. Studies conducted in academic health centers also make no claims about the random selection of practitioners or patients in their studies, although characteristics of those practitioners and patients are always described. PBRNs improve upon the generalizability of their study results because "real-world" practitioners are the ones doing the studies, under "real-world" conditions, and with patients who enter the non-academic health care system. Our earlier paper demonstrated that, although PBRNs do not take random samples, DPBRN dentists had much in common with dentists at large, and in fact the only characteristic that was statistically different from the ADA survey data was the number of years since graduation from dental school . This speaks to the generalizability of results from DPBRN studies. An additional next step is to demonstrate that participating practitioner-investigators comprise a diverse, broad range of backgrounds, practice environments, and patient populations, which also speak to the generalizability of results from DPBRN studies. The key value of the current study is that we are indeed able to demonstrate that diversity.
Our objective was to determine whether we met our network's goal to engage a diverse range of practitioner-investigators in DPBRN research. We can conclude that our objective was indeed met because we were able to document statistically significant and substantive differences in key characteristics within and between DPBRN regions, based on responses to the DPBRN Enrollment Questionnaire from dentists who participated in DPBRN's first network-wide study. These results illustrated the diversity of DPBRN practitioner-investigators, their practices, and their patient populations. These findings demonstrate that a very broad range of dentists and practices are participating in DPBRN.
This diversity will allow us to relate key practice characteristics to treatment outcomes in DPBRN studies, and whether results from these studies can be successfully incorporated into routine dental practice in a broad range of practice settings. DPBRN practices simultaneously comprise a diverse range of characteristics while also having much in common with practices at large . This within-network diversity and overall-network commonality to practices at large should increase the likelihood that DPBRN studies will be generalizable and applicable to other dental practices, thereby fostering knowledge transfer not only in the research-to-practice direction, but also in the practice-to-research direction.
This investigation was supported by National Institutes of Health, National Institute of Dental and Craniofacial Research grants U01-DE-16746 and U01-DE-16747. An Internet site devoted to details about DPBRN is located at http://www.DPBRN.org. The authors would like to thank Sha Zhu, Statistician, at the University of Alabama at Birmingham for his help with the DPBRN enrollment data and verification of analyses. Opinions and assertions contained herein are those of the authors and are not to be construed as necessarily representing the views of the respective organizations or the National Institutes of Health. The informed consent of all human subjects who participated in this investigation was obtained after the nature of the procedures had been explained fully. Persons who comprise the DPBRN Collaborative Group for this article are below:
Phil Adams, Sudhir Agarwal, Craig Ajmo, Lola Akinwale, Farshad Alamdari, Charles Allen, George Allen, Norman Allen, Catharina Amaloo, Craig Amundson, John Anderson, Damian Anderson, Gerald Anderson, Ronnie Arrington, Stanley Asensio, Stuart Atkinson, Karen Baker-Curtis, John Barnes, Michael Bauer, Mary Bell, Paul Benjamin, Per Bergmann, Wayne Berry, William Bishop, Hildegunn Bøckman, Kathleen Boehmke, Barry Booth, Charles Borden, Dorthe Borum, Thomas Bowen, Joel Boykin, Edward Bozeman, Joni Brackett, Bobby Bramblett, John Branstetter, Stephan Brewer, Galen Brey, W Timothy Brooks, Solomon Brotman, Brett Bruce, Lisa Bruce, Niels Brunn, Gitte Brunn, Robert Burks, Paul Bussman, James Callahan, R Calvert, Kimberly Carr, David Cawley, Jayne Cernohous, J Todd Chastain, Noel Childers, Kevin Cockrell, Emery Cole, Christina Congo, Robert Connor, Winton Cowles, C Michael Cowley, James Cox, Forrest Crabtree, Patrick Crow, Benjamin Cumbus, William Davis, Neel DeVos, Rodney Dellinger, Paul Dirkes, Camille Dixon, Christopher Donald, David Dotson, Catherine Dozier-Donald, Jessica Drapcho, James Dreading, Stuart Dropkin, James Duckworth, Michael Edwards, Geir Eide, Robert Embry, Harold Emmons, Marie Eng, R Dale Entrekin, Anita Fenn, William Findlay, Jerome Fiorella, Jay Fisher, Håkan Flink, Gull-Britt Fogelberg, George Ford, Johnny Foster, Patrick Foy, Ronald Friedensohn, William Fulton, J Larry Gafford, Geoff Gaunt, Daniel Gewartowski, Seth Gibree, Jeffery Gilbert, Roger Gill, Bennie Goggans, Gary Golden, Mark Gonsewski, Barry Goodspeed, Michelle Goodwyn, Farhad Gounili, James Gowen, Charles Graffeo, John Green, William Griffin, Asta Grinis, Paul Guidi, Martin Haedersdal, Beth Hairell Dillion, Charles Hall, Rex Hall, William Hall, Anders Hansen, Charlotte Hanson, Peter Harb, Forrest Harris, John Harrison, William Harrison, William Harrison, C Randy Harvell, Greg Hawkins, David Hazouri, Nancy Hein, Tim Herring, Wendy Holder, Bruce Holz, Gregory Horn, Robert Howard, Alex Howell, Susan Hudak Boss, Marie Hviid, George Hydrick, Benjamin Ingram, Shanaz Iranmanesh, Gordon Isbell, Janice Jackson, Marlon Jackson, John Jennings, Hoon Ji, Hiram Johnson, Teresa Johnson, Marc Johnson, Melodie Jones, Christopher Judson, Daniel Katz, Charles Keith, H. Paul Kellum, Jeffery Kendrick, Greg Kennedy, Allen Kessler, Byron Ketcham, John Keyton, David Kimmel, William King, Charles King, Jimmy King, Kurtis Klotzbuecher, Bruce Kneicht, George Kolos, Sally Lamberth, Sandra Lanter, Gary Lease, Greg Liebsch, Reginald Ligon, David Long, David Louis, Gary Lubel, Edgar Luna, Anton Luv, Steven Lynch, Michael Maddox, G Michael Maitre, Robert Maland, Robert Mallory, Michael Mann, Rodney Marshall, James Martin, James Martin, Daniel Mathers, George Matthews, Mark Maunter, William McClanahan, Jocelyn McClelland, Jennifer McClendon, Burton McGee, Ray McLaughlin, Ben McLeod, Robert Meador, V. Dale Meeks, Michael Meon, Jeffrey Meral, B Russell Methvin, Noah Miller, Mark Morelock, Diana Mortensen, Thomas Moseley, Jared Murrell, Gary Myers, Leigh Ann Nevins, Stephen New, John Nielsen, Eva Nordh, Hugh Ogletree, B. Linda Ongley, Ann O'Rear, Rikke Orlamundt, Per Påhlsson, Randall Palmore, William Pantazes, Jerry Parker, Tyrone Parrish, Wayne Patterson, Robert Payne, Liselotte Persson, Jim Phillips, Roberto Pischek, John Poczatek, Ted Poczatek, Marvin Poland, Lindsay Pope, Michael Precise, Wafa Qureshi, Karen Raleigh, Stephen Ray, A Rick Redmond, Ross Rehfeld, William Richardson, Vince Riehm, Matthew Rindal, Lloyd Ritchie, Louis Roque, Stephen Samson, Robert Sanderson, Jerome Scales, Lee Segrest, Manuel Serra-Jovenich, Sory Shannon, Sterling Shaw, M Shaw, Raymond Shenfield, Scott Shepard, Jerry Shiver, Alberto Silber, Frederick Smith, Harald Solem, Lotte Sørensen, Julian Sparks, Kenneth Springer, Art Steineker, Stephanie Steinmetz, James Stephans, Roxanna Stewart, Lyldon Strickland, Crawford Tatum, Timothy Tatum, Else Thiesson, Lars Thoegersen, Camilla Thoegersen, Lewis Thomas, Scott Thompson, Anibal Torres, L Riley Trehern, Russell Turner, Bill Turner, Helen Turner, Børge Vaadal, Walter Vickers, Richard Vining, Dale Vohler, Belinda Waldo, Thomas Walker, Mary Wallace, Martha Wallce, Jon Ward, Dave Watkins, Gerald Waxman, Paul Werner, Peter Westöö, Jimmy White, Shane Whitehead, Håkan Wickholm, Charles Wilkinson, Thomas Williams, David Winchester, Sonya Wintzell, Jeffrey Worley, Pia Worsøe, Morten Worsøe, Clayton Wright, Wilson Wright, Hugh Wunderlich, R Kurry Wyatt, Charles Yarbrough, Robin Yardic, Patrick Foy, Merry Jo Thoele, Jeffrey Fellows, Gail Morgan, Lisa Waiwaiole, Jackie Love, Andrea Mathews, Michelle Robinson, Sherry Sutphin, Kim Jenkins, Mark Litaker, Sharina Person, Dale Williams, Valerie Winston, Pia Nörrisgaard, Valeria Gordan, Pearl Harris, Deborah McEdward, Patti Moore, Joe Riley, and James Bader.
- Pearce KA, Love MM, Barron MA, Matheny SC, Mahfoud Z: How and why to study the practice content of a practice-based research network. Ann Fam Med. 2004, 2: 425-428. 10.1370/afm.133.PubMedView Article
- Fagnan LJ, Morris C, Shipman SA, Holub J, King A, Angier H: Characterizing a practice-based research network: Oregon rural practice-based research network (ORPRN) survey tools. J Am Board Fam Med. 2007, 20: 204-219. 10.3122/jabfm.2007.02.060140.PubMedView Article
- Mold JW, Peterson KA: Primary care practice-based research networks: working at the interface between research and quality improvement. Ann Fam Med. 2005, 3: S12-S20. 10.1370/afm.303.PubMedView Article
- Green LA, White LL, Barry HC, Nease DE, Hudson BL: Infrastructure requirements for practice-based research networks. Ann Fam Med. 2005, 3: S5-S11. 10.1370/afm.299.PubMedView Article
- Lenfant C: Clinical research to clinical practice: lost in translation?. New Engl J Med. 2003, 349: 868-874. 10.1056/NEJMsa035507.PubMedView Article
- Gilbert GH, Williams OD, Rindal DB, Pihlstrom DJ, Benjamin PL, Wallace MC, for the DPBRN Collaborative Group: The creation and development of the Dental Practice-Based Research Network. J Am Dent Assoc. 2008, 139: 74-81.PubMedView Article
- Green LA, Fryer GE, Yawn BP, Lainer D, Dovey SM: The ecology of medical care revisited. N Engl J Med. 2001, 344: 2021-2025. 10.1056/NEJM200106283442611.PubMedView Article
- Pihlstrom BL, Tabak L: The National Institute of Dental and Craniofacial Research. Research for the practicing dentist. J Am Dent Assoc. 2005, 136: 728-737.PubMedView Article
- Tabak LA: Dentistry on the road(map). J Am Dent Assoc. 2004, 135: 1362-1363.PubMedView Article
- Houston TK, Richman JS, Coley HL, Ray MN, Allison JJ, Gilbert GH, Gordan JS, Kiefe CI, for the DPBRN Investigator Group: Does delayed measurement affect patient reports of provider performance? Implications for performance measurement of tobacco cessation: a Dental PBRN study. BMC Health Services Research. 2008, 8: 1-8. 10.1186/1472-6963-8-100.View Article
- Mjör IA, Moorhead JE: Selection of restorative materials, reasons for replacement, and longevity of restorations in Florida. J Am Coll Dent. 1998, 65: 27-33.PubMed
- Qvist V, Qvist J, Mjör IA: Placement and longevity of tooth-colored restorations in Denmark. Acta Odontol Scand. 1990, 48: 305-11. 10.3109/00016359009033621.PubMedView Article
- Lando HA, Hennrikus D, Boyle R, Lazovich D, Stafne E, Rindal DB: Promoting tobacco abstinence among older adolescents in dental clinics. J Smoking Cessation. 2007, 2: 23-30. 10.1375/jsc.2.1.23.View Article
- Bader JD, Perrin NA, Maupomé G, Rindal DB, Rush WA: Validation of a simple approach to caries risk assessment. J Public Health Dent. 2005, 65: 76-81. 10.1111/j.1752-7325.2005.tb02790.x.PubMedView Article
- Green LA, Fryer GE, Froom P, Culpepper L, Froom J: Opportunities, challenges, and lessons of international research in practice-based research networks: the case of an international study of acute otitis media. Ann Fam Med. 2000, 2: 429-33. 10.1370/afm.224.View Article
- Makhija SK, Gilbert GH, Rindal DB, Benjamin P, Richman JS, Pihlstrom DJ, for the DPBRN Collaborative Group: Dentists in practice-based research networks have much in common with dentists at large: evidence from "The Dental PBRN". Gen Dent. 2009, 57: 270-275.PubMed
- Gilbert GH: Racial and socioeconomic disparities in health from population- based research to practice-based research: the example of oral health. J Dent Educ. 2005, 69: 1003-1014.PubMed
- Gilbert GH, Weems RA, Litaker MS, Shelton BJ: Practice characteristics associated with patient-specific receipt of dental diagnostic radiographs. Health Serv Res. 2006, 41: 1915-1937. 10.1111/j.1475-6773.2006.00537.x.PubMedView Article
- Gilbert GH, Bader JD, Litaker MS, Shelton BJ, Duncan RP: Patient-level and practice characteristics associated with receipt of preventive dental services: 48-month incidence. J Public Health Dent. 2008, 68: 209-217. 10.1111/j.1752-7325.2007.00069.x.PubMedView Article
- Gilbert GH, Shewchuk RM, Litaker MS: Effect of dental practice characteristics on racial disparities in patient-specific tooth loss. Med Care. 2006, 44: 414-420. 10.1097/01.mlr.0000207491.28719.93.PubMedView Article
- Gilbert GH, Litaker MS, Makhija SK: Differences in quality between dental practices associated with race and income mix of patients. J Health Care Poor Underserved. 2007, 18: 847-867.PubMedView Article
- Balas EA, Boren SA: Managing clinical knowledge for health care improvements. yearbook of Medical Informatics: Patient-Centered Systems. Edited by: Bemmel J, McCray AT. 2000, Stuttgart, Germany: Schattauer, 65-70.
- Green LA, Dovey SM: Practice-based primary care search networks: they work and they are ready for full development and support. Br Med J. 2001, 322: 567-568. 10.1136/bmj.322.7286.567.View Article
- Green LA, Hickner J: A short history of primary care practice-based research networks: from concept to essential research laboratories. J Am Board Fam Med. 2006, 19: 1-10. 10.3122/jabfm.19.1.1.PubMedView Article
- Tierney WM, Oppenheimer CC, Hudson BL, Benz J, Finn A, Hickner JM, Lanier D, Gaylin DS: A national survey of primary care practice-based research networks. Ann Fam Med. 2007, 5: 242-250. 10.1370/afm.699.PubMedView Article
- Westfall JM, Mold J, Fagnan L: Practice-based research-"Blue highways" on the NIH roadmap. J Am Med Assoc. 2007, 297: 403-406. 10.1001/jama.297.4.403.View Article
- Lindbloom EJ, Ewigman BG, Hickner JM: Practice-based research networks: the laboratories of primary care research. Med Care. 2004, 42 (Suppl 4): III45-1149.PubMed
- Thomas P, Griffiths K, Kai J, O'Dwyer A: Networks for research in primary health care. BMJ. 2001, 322: 588-590. 10.1136/bmj.322.7286.588.PubMedView Article
- Slora EJ, Thoma KA, Wassweman RC, Pedlow SE, Bocian AB: Patient visits to a national practice-based research network: comparing pediatric research in office settings with the national ambulatory medical care survey. Pediatrics. 2006, 118: 228-234. 10.1542/peds.2005-0701.View Article
- Burgess K, Ruesch JD, Mikkelsen MC, Wagner KS: ADA members weigh in on critical issues. J Am Dent Assoc. 2003, 134: 103-107.PubMedView Article
- The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1472-6831/9/26/prepub
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.