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Table 1 Descriptive data of the study subjects divided in groups according to the use of hormone replacement therapy (HRT).

From: Periodontal disease-associated micro-organisms in peri-menopausal and post-menopausal women using or not using hormone replacement therapy. A two-year follow-up study

  Baseline Two-year follow-up
  HRT (106) Non-HRT (55) Significance
between groups
HRT (106) Non-HRT (55) Significance between groups
Mean age 55.4 ± 2.7 55.9 ± 2.4 ns. 57.4 ± 2.7 57.9 ± 2.4 ns.
Current smoker 23(22%) 11(20%) ns. 19(18%) 8 (15%) ns.
Current climateric symptoms 16 (15%) 24 (44%) p < 0.001 14 (13%) 19 (35%) p < 0.001
Satisfactory self-assesed dental health 65 (61%) 28 (51%) ns. 63 (59%) 31 (56%) ns.
Diagnosed illness:       
Cardiovascular disease 19 (18%) 10 (18%) ns. 25 (24%) 11 (20%) ns.
Psychiatric disease 1 (1%) 2 (4%) ns. 1 (1%) 3 (6%) ns.
Asthma 8 (8%) 3 (6%) ns. 12 (11%) 3 (6%) ns.
Rheumatic disease 8 (8%) 2 (4%) ns. 6 (6%) 3 (6%) ns.
Regular medication:       
Use of cardiovascular drugs# 29 (27%) 14 (26%) ns. 39 (37%) 14 (26%) ns.
Use of neurological drugs# 7 (7%) 10 (18%) p < 0.05 5 (5%) 9 (16%) p < 0.05
Use of respiratory drugs# 7 (7%) 4 (7%) ns. 15 (14%) 4 (7%) ns.
Use of analgesics and antipyretics 7 (7%) 1 (2%) ns. 5 (5%) 5 (9%) ns.
Allergy medication 4 (4%) 0 (0%) ns. 0 0 -
Oestrogen therapy 49 (47%)    47 (47%)   
Progestin therapy 2 (2%)    1 (1%)   
Combination therapy 53 (51%)    53 (53%)   
  1. Ns. = Statistical difference non-significant.
  2. #Includes diuretics, antihypertensive agents, nitrates, digitalis and antiarrhythmic agents;
  3. ##Includes antidepressant drugs, tranquilizers, sedatives and antipsychotic agents;
  4. ### Mainly medication for asthma.