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Table 1 Descriptive data of the study subjects divided in groups according to the use of hormone replacement therapy (HRT).

From: Periodontal disease-associated micro-organisms in peri-menopausal and post-menopausal women using or not using hormone replacement therapy. A two-year follow-up study

 

Baseline

Two-year follow-up

 

HRT (106)

Non-HRT (55)

Significance

between groups

HRT (106)

Non-HRT (55)

Significance between groups

Mean age

55.4 ± 2.7

55.9 ± 2.4

ns.

57.4 ± 2.7

57.9 ± 2.4

ns.

Current smoker

23(22%)

11(20%)

ns.

19(18%)

8 (15%)

ns.

Current climateric symptoms

16 (15%)

24 (44%)

p < 0.001

14 (13%)

19 (35%)

p < 0.001

Satisfactory self-assesed dental health

65 (61%)

28 (51%)

ns.

63 (59%)

31 (56%)

ns.

Diagnosed illness:

      

Cardiovascular disease

19 (18%)

10 (18%)

ns.

25 (24%)

11 (20%)

ns.

Psychiatric disease

1 (1%)

2 (4%)

ns.

1 (1%)

3 (6%)

ns.

Asthma

8 (8%)

3 (6%)

ns.

12 (11%)

3 (6%)

ns.

Rheumatic disease

8 (8%)

2 (4%)

ns.

6 (6%)

3 (6%)

ns.

Regular medication:

      

Use of cardiovascular drugs#

29 (27%)

14 (26%)

ns.

39 (37%)

14 (26%)

ns.

Use of neurological drugs#

7 (7%)

10 (18%)

p < 0.05

5 (5%)

9 (16%)

p < 0.05

Use of respiratory drugs#

7 (7%)

4 (7%)

ns.

15 (14%)

4 (7%)

ns.

Use of analgesics and antipyretics

7 (7%)

1 (2%)

ns.

5 (5%)

5 (9%)

ns.

Allergy medication

4 (4%)

0 (0%)

ns.

0

0

-

Oestrogen therapy

49 (47%)

  

47 (47%)

  

Progestin therapy

2 (2%)

  

1 (1%)

  

Combination therapy

53 (51%)

  

53 (53%)

  
  1. Ns. = Statistical difference non-significant.
  2. #Includes diuretics, antihypertensive agents, nitrates, digitalis and antiarrhythmic agents;
  3. ##Includes antidepressant drugs, tranquilizers, sedatives and antipsychotic agents;
  4. ### Mainly medication for asthma.