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Table 3 Predominant pathogens isolated from oral cavity of neutropenic and non-neutropenic patients treated with radiotherapy, chemotherapy and radiochemotherapy (Group I, II, III)

From: Incidence and risk factors for infection in oral cancer patients undergoing different treatments protocols

Pathogens

ANC (<500) ANC(>500)

ANC(<500)ANC(>500)

ANC(<500)ANC(>500)

 

n = 61

n = 82

OR (95 % C.I)

P

n = 79

n = 57

OR (95 % C.I)

P

n = 92

n = 83

OR (95 % C.I)

P

(A)Gram + ive

13(21.3)

12(14.6)

1.58(0.61-4.0)

0.41

25(31.6)

18(31.5)

1.00(0.45-2.2)

0.85

39(42.3)

31(37.3)

1.23(0.6-2.3)

0.59

S. aureus

8(13.1)

6(7.3)

1.60(0.25-10.7)

0.85

18(22.7)

11(19.2)

1.64(0.38-7.2)

0.67

29(31.5)

15(18)

3.09(1.0-9.6)

<0.05*

S. epidermidis

5(8.1)

6(7.3)

0.63(0.09-4.0)

0.85

7(8.8)

7(12.28)

0.61(0.14-2.2)

0.67

10(10.8)

16(19.2)

0.32(0.1-0.9)

<0.05*

(B)Gram -ive

20(32.9)

18(21.9)

1.25(0.57-2.7)

0.68

43(54.4)

33(57.8)

0.87(0.41-1.8)

0.82

22(23.9)

29(34.9)

0.59(0.2-1.1)

0.15

E. coli

4(6.5)

6(7.3)

0.50(0.09-2.6)

0.46

7(8.8)

8(14.3)

0.61(0.17-2.1)

0.56

6(6.5)

8(9.6)

0.98(0.2-4.0)

.77

P. aeruginosa

3(4.9)

4(4.8)

0.62(0.09-4.1)

0.68

5(6.3)

4(7)

0.95(0.20-4.7)

1.00

5(5.4)

7(8.4)

0.92(0.2-4.0)

0.82

K. pneumonia

5(8.1)

5(6.0)

0.87(0.16-4.5)

1

27(34.1)

13(22.8)

2.60(0.93-7.3)

< 0.05*

4(4.3)

5(6)

1.07(0.2-5.5)

1

P. mirabilis

5(8.1)

3(3.6)

3(0.41-26.4)

0.40

4(5.0)

6(10.5)

0.46(0.10-2.1)

0.31

4(4.3)

5(6)

1.07(0.2-5.5)

1

P. vulgaris

3(3.8)

0

UN

0.23

0

2(3.5)

0.00(0.00-3.14)6

0.18

3(3.2)

4(4.8)

0.99(0.1-6.1)

1

(C) Fungi

28(45.9)

52(63.4)

0.49(0.24-1.0)

< 0.05*

11(13.9)

6(10.5)

1.38(0.43-4.5)

0.74

31(33.6)

23(27.7)

1.33(0.6-2.6)

0.48

C. albicans

28(45.9)

40(48.7)

1.30 (1.12-1.5)

< . 001***

7(8.8)

6(10.5)

0.00(0.00-2.8)

0.23

26(28.2)

23(27.7)

0.00(0.0-1.5)

<.05*

A. fumigatus

0

12

UN

.02

4(5.0)

0

UN

1.0

5(5.4)

0

UN

1

  1. Note: n = number of pathogens, UN: Undefined, % had been shown in parenthesis, ANC = absolute neutrophil count, ANC of <500 neutrophil/micro L (neutropenic), ANC >500 neutrophil/micro L (non-neutropenic). P = Probability value with an ANC of <500 neutrophil/micro L (neutropenic) vs. those with ANC >500 neutrophil/micro L (non-neutropenic). P < .05 * less significant, P < .01 ** significant, P < .001 *** highly significant.