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Table 5 Predominant pathogens isolated from blood of neutropenic and non-neutropenic patients treated with radiotherapy, chemotherapy and radio-chemotherapy (Group I, II. III)

From: Incidence and risk factors for infection in oral cancer patients undergoing different treatments protocols

Pathogens

ANC (<500) ANC(>500)

ANC(<500)ANC(>500)

ANC(<500)ANC(>500)

 

n = 64

n = 85

OR (95 % C.I)

P

n = 90

n = 55

OR (95 % C.I)

P

n = 112

n = 95

OR (95 % C.I)

P

(A)Gram + ive

23(35.9)

18(21.1)

2.09(0.95-4.6)

0.07

52(5.7)

25(45.4

1.64(0.7-3.4)

0.20

61( 54.4)

35(36.8)

2.0(1.1-3.7)

< 0.01**

S. aureus

15(23.4)

12(14.1)

0.94(0.21-4.1)

0.81

42(4.6)

11(2)

5.35 (1.6-17.6)

< .001**

21( 18.7)

28(29.4)

0.1(0.0-0.3)

< .001***

S. epidermidis

8(12.5)

6(7.0)

1.07(0.24-4.7)

0.81

10(1.1)

14(25.4)

0.19(0.0-0.6)

< .001**

40(35.7)

7(7.3)

7.6(2.6-23.1)

< .001***

(B)Gram -ive

26(40.6)

56(65.8)

0.35(0.1-0.7)

< 0.001***

24(2.6)

22(4)

0.55(0.2-1.1)

0.13

39(34.8)

42(44.2)

0.67(0.3-1.2)

0.21

E. coli

10(15.6)

9(10.5)

0.34(0.1-0.9)

0.04

7(7.7)

6(10.9)

1.10(0.2-4.7)

0.85

11(9.8)

17(17.8)

0.58(0.2-1.6)

0.35

P. aeruginosa

6(9.3)

28(32.9)

0.30(0.0-0.9)

< 0.05*

7(7.7)

7(12.7)

0.88(0.2-3.7)

0.90

12(10.7)

12(12.6)

1.11(0.3-3.2)

0.97

K. pneumonia

5(7.8)

14(16.4)

0.71(0.1-2.5)

0.76

6(6.6)

5(9.0)

1.13(0.2-5.4)

0.86

10(8.9)

7(7.3)

1.72(0.5-5.8)

0.47

P. mirabilis

5(7.8)

5(5.8)

2.43(0.5-11.1)

0.27

4(4.4)

3(5.4)

1.27(0.2-8.4)

1.00

4(3.5)

5(5.2)

0.85(0.1-4.0)

1

P. vulgaris

0

0

0

0

0

1(1.8)

0.00(0.0-16.4)

0.47

2(1.7)

1(1.0)

1.84(0.1-53.7)

1

(C) Fungi

15(23.4)

11(12.9)

2.06(0.8-5.2)

0.14

14(15. 5)

8(14.5)

1.20(0.4-3.3)

0.88

12(10.7)

18(18.9)

0.51(0.2-1.2)

0.13

C. albicans

9(14.0)

6(7.0)

1.25(0.2-8.0)

1.00

8(8.8)

5(9.0)

0.80(0.0-6.5)

1.00

7(6.2)

10(10.5)

1.12(0.2-6.3)

0.82

A. fumigatus

6(9.3)

5(5.8)

0.80(0.1-5.0)

1.00

6(6.6)

3(5.4)

1.25(0.1-10.5)

1.00

5(4.4)

8(8.4)

0. 89(0.1-4.9)

0.82

  1. Note: n = number of pathogens, % had been shown in parenthesis, ANC = absolute neutrophil count, ANC of <500 neutrophil/micro L (neutropenic), ANC > 500 neutrophil/micro L (non-neutropenic). P = Probability value of patients with an ANC of <500 neutrophil/micro L (neutropenic) vs. those with ANC >500 neutrophil/micro L (non-neutropenic). P < .05 * less significant, P < .01 ** significant, P < .001 *** highly significant.