From: Short term serum pharmacokinetics of diammine silver fluoride after oral application
Subject | Body weight (kg) | Weight of DSF solution applied (mg) | Calculated volume of DSF solution applied (μL)a | Calculated fluoride applied (mg)b | Fluoride - oral RfDcNOAELdfor subject (mg)e | Time to maximum serum concentration (h) | Maximum serum fluoride (μmol/L) |
---|---|---|---|---|---|---|---|
1 | 48 | 3.8 | 3.03 | 0.17 | 2.88 | 3.0 | 1.46 |
2 | 54 | 8.2 | 6.54 | 0.36 | 3.24 | 3.2 | 2.88 |
3 | 84 | 5.8 | 4.63 | 0.25 | 5.04 | 4.0 | 1.02 |
4 | 82 | 7.6 | 6.07 | 0.33 | 4.92 | 3.0 | 2.77 |
5 | 54 | 11.9 | 9.50 | 0.52 | 3.24 | 1.0 | 1.56 |
6 | 56 | 8.1 | 6.46 | 0.36 | 3.36 | 4.0 | 1.45 |