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Table 1 Susceptibility profile of clinically relevant oral bacteria to four antimicrobial agents

From: Investigating the biological properties of carbohydrate derived fulvic acid (CHD-FA) as a potential novel therapy for the management of oral biofilm infections

MIC (%)
  CHD-FA CHX
Organism PMIC MBC SMIC Fold change PMIC MBC SMIC Fold change
     (SMIC/PMIC)     (SMIC/PMIC)
A. a * 0.25 0.25 0.5 2 0.00078 0.00313 0.025 32
S. mitis 0.0625 0.125 0.5 8 0.00078 0.00156 0.0125 16
S. mutans 0.25 0.25 0.5 2 0.00039 0.00078 0.025 64
E. faecalis 0.125 0.25 0.5 4 0.00156 0.025 0.003 2
F. nucleatum 0.125 0.5 0.5 4 0.00039 0.00078 0.195 32
P. gingivalis 0.0625 0.5 0.5 8 ≤0.00039 0.00078 0.0625 ≥16
  1. *A. actinomycetemcomitans.
  2. CHD-FA - (Fulhold Ltd, South Africa), CHX - (GlaxoSmithKline Consumer Health Care, UK).