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Table 5 Changes in mean HbA1c and CRP for subjects with good response to periodontal treatment in OHI and NSPT groups

From: Effect of nonsurgical periodontal therapy verses oral hygiene instructions on Type 2 diabetes subjects with chronic periodontitis: a randomised clinical trial

Reduction of periodontal parameters after treatment Baseline 3 months p-value Effect size (ES)
  HbA1c hs-CRP HbA1c hs-CRP p1 p2 ES1 ES2
  (mean ± SD mmol/mol ± SD) (mean ± SD) (mean ± SDmmol/mol ± SD) (mean ± SD)     
Subjects with a 50% reduction in plaque index scores (n = 7) 8.2 ± 1.1 66 ± 9 5.3 ± 3.6 7.1 ± 1.6 57 ± 12 4.9 ± 3.6 0.065 0.666 0.853 0.171
Subjects with a 50% reduction in gingival bleeding scores (n = 2) 9.0 ± 0.3 75 ± 2 10.0 ± 0.4 7.7 ± 0.4 60 ± 3 8.1 ± 0.9 0.205 0.289 2.121 1.452
Subjects with a 50% reduction in mean PPD (n = 16) 7.7 ± 1.4 60 ± 11 9.6 ± 14.6 6.8 ± 0.8 51 ± 6 8.2 ± 12.9 0.004 0.012 0.859 0.710
  1. p1 - p value of HbA1c between baseline and 3 months.
  2. p2 - p values of hs-CRP between baseline and 3 months.
  3. ES1 - effect size of HbA1c from baseline to 3 months.
  4. ES2 - effect size of hs-CRP from baseline to 3 months.