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Table 2 Primary caries prevention: prevented fraction in permanent teeth and quality of evidence for non-fluoride measures

From: The evidence base for professional and self-care prevention - caries, erosion and sensitivity

Method Prevented fractiona Quality of evidenceb Reference No.
Self-care    
Xylitol gums 59% OO [12, 13]
Triclosan/copolymer toothpaste 5% 14
Interdental cleaning (brushing and flossing) 24% OOO [15, 16]
Professional care    
Fissure sealants 84-65%c O [17, 18]
Chlorhexidine varnish 21% OOO [19, 20]
Silver diamine fluoride (38%) 70% OO [21, 22]
Ozone NDd OOO [23]
Oral health counselling, motivational interviews ND OOO [24, 25]
Dietary intervention ND OOO [26]
Early age preventive dental visits, Recall intervals ND OOO [2729]
  1. a prevented fraction = difference in caries increment between a test and a control group, divided by the mean caries increment in the control group
  2. b according to the GRADE-scale, see Table 1.
  3. c 2-9 year follow-up
  4. d ND = not determined?