Table 4 Frequency (and percentage of the total) of malformations by affected organ systems in subjects with multiple congenital anomalies.
From: Oral clefts with associated anomalies: findings in the Hungarian Congenital Abnormality Registry
CL/P (n= 436) | CP (n= 217) | Both (n= 653) | |
|---|---|---|---|
Central nervous system | 158 (20.6) | 44 (11.1) | 202 (17.4) |
Eye | 36 (4.7) | 7 (1.8) | 44 (3.8) |
Ear | 32 (4.2) | 23 (5.8) | 55 (4.7) |
Face-neck | 16 (2.1) | 22 (5.5) | 38 (3.3) |
Cardiovascular system | 119 (15.6) | 75 (18.9) | 194 (16.7) |
Respiratory system | 4 (0.5) | 4 (1.0) | 8 (0.7) |
Digestive system | 51 (6.7) | 30 (7.5) | 81 (7.0) |
Urogenital system | 88 (11.5) | 44 (11.1) | 132 (11.3) |
Skeletal (including limb deficiency) | 191 (25.0) | 121 (30.5) | 312 (26.8) |
Skin | 0 (0.0) | 1 (0.2) | 1 (0.1) |
Abdominal wall/diaphragma | 46 (6.0) | 15 (3.8) | 61 (5.2) |
Other† | 24 (3.1) | 11 (2.8) | 35 (3.0) |
Total number of malformations | 765 | 397 | 1,162 |