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Table 2 Association of selected variables or markers with caries.

From: Improved ability of biological and previous caries multimarkers to predict caries disease as revealed by multivariate PLS modelling

   

PLS associationsa

x variables or markers

 

unitsb

Baseline

Increment

Incidence

Progression

   

VIP

coeff

VIP

coeff

VIP

coeff

VIP

coeff

P REVIOUS CARIES c

   Decayed, smooth surfaces

 

numbers/subj

  

2.049

+

2.221

+

2.752

+

   Decayed and Filled, all surfaces

 

-"-

  

1.785

+

1.946

+

2.204

+

   Decayed, all surfaces

 

-"-

  

1.979

+

2.187

+

2.427

+

   Decayed, proximal surfaces

 

-"-

  

1.758

+

1.841

+

2.652

+

   Filled, all surfaces

 

-"-

  

1.478

+

1.648

+

1.705

+

   Filled, occlusal surfaces

 

-"-

  

1.239

+

1.383

+

1.576

+

P LAQUE d

          

   Lactobacilli

saliva

CFU/ml

2.494

+

1.177

+

1.078

+

1.982

+

 

plaque

%

2.244

+

1.601

+

1.707

+

2.041

+

   Mutans streptococci

saliva

CFU/ml

1.066

+

0.91

+

0.94

+

0.47

+

 

plaque

%

1.142

+

1.104

+

1.214

+

1.266

+

   Plaque amount

 

%

0.63

+

0.94

+

1.020

+

0.76

+

   Plaque formation rate

 

slow/rapid

0.47

 

0.98

-

0.46

-

0.72

-

   Plaque fluoride

 

ug/g wet plaque

1.117

-

0.75

-

0.88

-

0.58

-

D IET e

          

   Zinc

 

mg/day

1.016

-

1.063

-

1.194

-

0.50

-

   Lauric acid (12:0)

 

g/day

1.115

-

1.162

-

1.320

-

0.87

-

   Calcium

 

mg/day

0.92

-

1.317

-

1.750

-

0.004

-

   Riboflavin

 

mg/day

1.02

 

1.047

-

1.314

-

0.27

-

   Phosphate

 

mg/day

1.05

 

1.090

-

1.320

-

0.16

-

   Protein

 

g/day

1.05

 

1.014

-

1.202

-

0.19

-

   Retinol equivalents (vit A)

 

mg/day

1.307

-

0.96

-

1.102

-

0.74

-

   Buturic acid (4:0)

 

g/day

0.80

-

0.93

-

1.185

-

0.56

-

   Linoleic acid (18:2)

 

g/day

1.122

-

0.92

 

0.60

-

0.29

-

   Folate

 

ug/day

1.001

-

0.99

-

1.130

-

0.80

-

   Vitamin E

 

mg/day

1.033

-

0.95

-

0.89

-

0.72

-

   Iron

 

mg/day

0.97

 

1.038

+

0.43

+

0.08

-

   Carbohydrates (total)

 

g/day

1.10

 

1.253

+

0.80

+

0.28

+

   Fiber

 

g/day

0.77

-

1.193

+

0.58

+

0.22

-

   Energy

 

kcal/day

1.19

 

0.98

+

0.08

+

0.07

-

   Monosaccharides

 

g/day

0.61

-

0.48

+

0.06

-

0.56

-

   Sucrose

 

g/day

1.08

 

0.87

+

0.43

+

0.37

+

S ALIVA f

          

   Parotid, stimulated

          

Calcium

 

mmol/ml

1.188

-

0.63

-

0.51

-

1.111

-

Phosphate

 

mmol/ml

0.97

 

1.251

-

1.260

-

0.25

+

Aggregation by S. mutans

 

m-value

0.85

+

0.65

+

0.80

+

0.41

+

S-IgA

 

ug/ml

1.18

 

0.30

-

0.03

-

0.47

+

Lysozyme

 

ug/ml

0.51

+

0.75

-

0.08

-

0.80

-

Peroxidase

 

activity/ml

0.40

+

0.40

+

0.54

+

0.54

-

Thiocyanate

 

mmol/ml

0.55

 

0.19

-

0.14

-

0.43

+

Flow rate

 

ml/min

1.03

 

1.020

+

1.155

+

0.35

-

   Whole saliva, stimulated

          

Flow rate

 

ml/min

1.00

 

0.36

-

0.22

-

1.081

-

pH

 

pH

0.50

 

0.39

-

0.34

-

0.20

-

Buffer capacity

 

final pH

0.61

 

0.77

-

0.88

-

0.40

-

  1. ab Primary PLS models M1 to M4. VIP values > 1.0 marks influential variables (see Methods). Consistent positive (+) or negative (-) association for the regression coefficients for each y variable; otherwise blank.
  2. b Variable units and units of measures used for derived variables.
  3. c Some of the previous caries x variables (n = 18) derived from the y1-y18 baseline caries variables (see Methods).
  4. d The plaque variables except for phosphate and plaque % of lbc+/ms+, lbc+/ms- or lbc-/ms+ (see Methods).
  5. e Some of the 45 diet variables (see Methods).
  6. f The whole saliva variables except for chewing rate. The parotid saliva variables except for the same factors in resting parotid saliva and derived secretion rates for some components in both salivas (see Methods).