Table 2 Clinical and biomedical variables in blood serum of the subjects with or without pathological periodontal pockets (PD ≥4 mm)

Presence of dental calculus

 Supragingival

8 (57)

22 (36)

0.151

 Subgingival

4 (29)

10 (16)

0.586

VPI

 0-25%

8(57)

47 (77)

 > 25%

6 (43)

14 (23)

0.132

BOP

 0-25%

5 (36)

47 (77)

 > 25%

9 (64)

1 (23)

0.002

Mean (SD)

Mean (SD)

Adiponectin (μg/ml)

13.5 (74.3)

12.3 (802)

0.641

PAI-1 Tot (ng/ml)

42.8 (19.2)

944 (6635)

0.642

IL-1β (pg/ml)

0.8 (0.8)

1.1 (4.1)

0.819

IL-6 (pg/ml)

37.5 (44.9)

10.5 (11.3)

<0.001

IL-8 (pg/ml)

15.2 (7.7)

33.9 (106.8)

0.548

Leptin (ng/ml)

66.3 (54,1)

41.2 (23.0)

0.018

TNF-α (pg/ml)

6.9 (2.5)

6.8 (3.1)

0.848

MCP-1 (pg/ml)

256 (104)

464 (352)

0.049

Total cholesterol (mmol/l)

3.9 (0.7)

4.0 (0.7)

0.645

LDL/HDL quotient

2.1 (1.0)

2.2 (0.7)

0.404

Hba1c (mmol/mol)

4.5 (0.4)

4.6 (0.4)

0.182

CRP (mg/l)

2.6 (2.7)

4.7 (4.1)

0.071

TSH (mlU/l)

3.9 (3.0)

2.5 (1.1)

0.004

Blood pressure (mmHg)

 -Systolic

119 (9)

116 (9)

0.294

 -Diastolic

74 (5)

67 (7)

0.008

Insulin resistance Bergman

 -Si (×10⁻⁴/min/pM)

1.9 (1.3)

1.5 (1.4)

0.313

 -Air (pM)

1930 (1782)

3107 (3692)

0.254