Missense mutation | Controls (n = 121) | Cases (n = 121) | x 2 | P-value* | COR (95% CI) | P-value | ||
---|---|---|---|---|---|---|---|---|
n (%) | n (%) | |||||||
23 G → A† | 5 | (4.1) | 12 | (9.9) | 3.100 | 0.078 | 2.55(0.87-7.49) | 0.087 |
34 A → G | 7 | (5.8) | 10 | (8.3) | 0.569 | 0.450 | 0.68(0.25-1.85) | 0.453 |
36 T → C | 6 | (5.0) | 11 | (9.1) | 1.582 | 0.209 | 1.92(0.69-5.36) | 0.215 |
47 C → T | 8 | (6.6) | 11 | (9.1) | 0.514 | 0.473 | 1.41(0.55-3.64) | 0.475 |
100 C → T | 0 | (0.0) | 1 | (0.8) | — | 1.000** | — | 1.000 |
112 G → A | 71 | (58.7) | 71 | (58.7) | 0.000 | 1.000 | 1.00(0.60-1.67) | 1.000 |
114 C → T | 65 | (53.7) | 56 | (46.3) | 1.339 | 0.247 | 0.74(0.45-1.23) | 0.248 |
168 T → G | 26 | (21.5) | 13 | (10.7) | 5.166 | 0.023 | 0.44(0.21-0.90) | 0.025 |
176 A → G | 63 | (52.1) | 68 | (56.2) | 0.416 | 0.519 | 1.18(0.71-1.96) | 0.519 |
256 G → T | 1 | (0.8) | 0 | (0.0) | — | 1.000** | — | 1.000 |
298 G → A | 1 | (0.8) | 0 | (0.0) | — | 1.000** | — | 1.000 |
382 G → A | 1 | (0.8) | 0 | (0.0) | — | 1.000** | — | 1.000 |
470 G → A | 7 | (5.8) | 17 | (14.0) | 4.625 | 0.032 | 2.66(1.06-6.68) | 0.037 |
548 T → C | 0 | (0.0) | 1 | (0.8) | — | 1.000** | — | 1.000 |
584 C → T | 0 | (0.0) | 1 | (0.8) | — | 1.000** | — | 1.000 |
671 A → C | 115 | (95.0) | 116 | (95.9) | 0.095 | 0.758 | 0.83(0.25-2.78) | 0.758 |
706 G → A | 0 | (0.0) | 1 | (0.8) | — | 1.000** | — | 1.000 |