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Table 5 Bivariate analysis of the missense mutation rates in relation to caries status

From: Genetic polymorphisms of the sortase A gene and social-behavioural factors associated with caries in children: a case–control study

Missense mutation

Controls (n = 121)

Cases (n = 121)

x 2

P-value*

COR (95% CI)

P-value

n (%)

n (%)

23 G → A

5

(4.1)

12

(9.9)

3.100

0.078

2.55(0.87-7.49)

0.087

34 A → G

7

(5.8)

10

(8.3)

0.569

0.450

0.68(0.25-1.85)

0.453

36 T → C

6

(5.0)

11

(9.1)

1.582

0.209

1.92(0.69-5.36)

0.215

47 C → T

8

(6.6)

11

(9.1)

0.514

0.473

1.41(0.55-3.64)

0.475

100 C → T

0

(0.0)

1

(0.8)

1.000**

1.000

112 G → A

71

(58.7)

71

(58.7)

0.000

1.000

1.00(0.60-1.67)

1.000

114 C → T

65

(53.7)

56

(46.3)

1.339

0.247

0.74(0.45-1.23)

0.248

168 T → G

26

(21.5)

13

(10.7)

5.166

0.023

0.44(0.21-0.90)

0.025

176 A → G

63

(52.1)

68

(56.2)

0.416

0.519

1.18(0.71-1.96)

0.519

256 G → T

1

(0.8)

0

(0.0)

1.000**

1.000

298 G → A

1

(0.8)

0

(0.0)

1.000**

1.000

382 G → A

1

(0.8)

0

(0.0)

1.000**

1.000

470 G → A

7

(5.8)

17

(14.0)

4.625

0.032

2.66(1.06-6.68)

0.037

548 T → C

0

(0.0)

1

(0.8)

1.000**

1.000

584 C → T

0

(0.0)

1

(0.8)

1.000**

1.000

671 A → C

115

(95.0)

116

(95.9)

0.095

0.758

0.83(0.25-2.78)

0.758

706 G → A

0

(0.0)

1

(0.8)

1.000**

1.000

  1. *Chi-square test. **Fisher’s exact test.
  2. G → A, G represents the 23 locus base in UA159, A represents the 23 locus base in the clinical strains.
  3. COR (crude odds ratio), CI (confidence interval).