The concomitant administration of systemic amoxicillin and metronidazole compared to scaling and root planing alone in treating periodontitis: =a systematic review=

Table 4 Estimated evidence profile (GRADE, 2014) and appraisal of the strength of the recommendation

Determinants of the Quality		PPD mean	CAL mean
Study design		RCT, CCT	RCT, CCT
Risk of bias (methodological limitations)		Low to high	Low to high
Consistency		Rather consistent	Inconsistent
Directness		Generalizable	Generalizable
Precision		Precise	Precise
Reporting bias		Possible	Possible
Magnitude of the effect	Overall mean	Moderate	Moderate
Magnitude of the effect	Pockets initially ≥ 6 mm	Large	Large
Strength of the recommendation based on the quality and body of evidence		Strong	Moderate

ISSN: 1472-6831