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Table 3 Hazard ratios (HR) for the influence of health behavior variables on tumor survival in HNSCC patients

From: Pretreatment oral hygiene habits and survival of head and neck squamous cell carcinoma (HNSCC) patients

Variable

HR overall survivala

 

HR progression free survivala

 

HR tumorspecific survivala

 

(n = 263)

95 % CI

(n = 254)

95 % CI

(n = 261)

95 % CI

Dental care scoreb

 Score 0–2

1.00

Ref.

1.00

Ref.

1.00

Ref.

 Score 3–6 (poor care)

1.30

0.78–2.15

1.48

0.89–2.45

1.51

0.79–2.88

Mouthwash used

 Mouthwash < 2 times/day

1.00

Ref.

1.00

Ref.

1.00

Ref.

 Mouthwash ≥ 2 times/day

1.32

0.76–2.31

1.47

0.88–2.47

2.26

1.19–4.32

Oral health scorec

 Oral health 0–5

1.00

Ref.

1.00

Ref.

1.00

Ref.

 Oral health 6–7 (poor health)

1.05

0.69–1.60

1.11

0.74–1.67

0.85

0.47–1.54

Smoking log[pack-years + 1]

 10 pack-years

2.05

1.17–3.61

1.89

1.11–3.24

1.72

0.83–3.56

 20 pack-years

2.46

1.21–4.97

2.22

1.14–4.34

1.97

0.79–4.89

Smoking freq log[cigarettes + 1]

 10 cigarettes/day

2.30

1.17–4.52

2.04

1.07–3.89

2.06

0.83–5.09

 20 cigarettes/day

2.83

1.22–6.58

2.44

1.09–5.46

2.47

0.80–7.64

Drinking (drink-years) log[drinkyears + 1]

 10 drink-years

1.59

1.14–2.24

1.53

1.10–2.11

1.90

1.21–2.99

 20 drink-years

1.79

1.17–2.74

1.70

1.13–2.55

2.23

1.27–3.93

Drinking freq log[drinks + 1]

 2 drinks/day

1.47

1.13–1.90

1.52

1.18–1.97

1.52

1.08–2.12

 5 drinks/day

1.87

1.22–2.87

1.99

1.31–3.04

1.97

1.14–3.41

  1. Bold numbers indicate statistically significant log rank tests and HR
  2. Abbreviations: freq frequency, log logarithmic transformation, Ref reference
  3. aHazard ratios: Cox regression model adjusted for age, sex, tumor site, tumor stage, treatment, education, smoking, alcohol drinking, HPV status. Hazard ratios describe the risk of death, tumor progression or tumor specific death within the observational period; bincludes information on brushing teeth, use of floss, dentist visits cincludes information on wearing dentures, age at wearing dentures, gum bleeding; dindependent variable