Study | Country | Subjects (Laser/ Placebo/ Control) Age (yrs) Gender (M/F) | Study design | Orthodontic treatment | Placebo/ Control group | Measurement | Results (laser group, LG, Control group, C) | Type of laser | Wavelength (nm) | Time per point/ Total time per treatment | Frequency of laser treatment | Power (mW) | Dose (J/cm2) | Time per point/ Total time per treatment | Frequency of laser treatment |
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Doshi-Meht [7] (2012) | India | 20/20 12–23 y 8/12 | Single blinded RCT (Split mouth) | Maxillary and mandibular canine retraction NiTi closed-coil spring | Placebo | Digital caliper on model | Mean increased tooth movement rate end of 3 month: LG: Maxilla; 54 %. Mandible; 58 % Mean increased tooth movement rate at complete retraction LG: Maxilla; 29 %, Mandible; 31 % | AlGaAs | 800 | 10 s/1 min 40 s | Day 3, 7, and 14 in the first month. Thereafter on every 15th day until complete canine retraction on the experimental side, average 4.5 month | 0,25 | 5 | 10 s/Unclear | Day 3, 7, and 14 in the first month. Thereafter on every 15th day until complete canine retraction on the experimental side, average 4.5 month. |
Genc [9] (2013) | Turkey | 20/20 17,8 y 6/14 | Unblinded CCT (Split mouth) | Maxillary canine retraction NiTi closed coil spring (mini-implant) | Control | Digital calliper | Tooth movement LG; 20–40 % faster than C. | GaAlAs | 808 | 10 s/1 min 40 s | Day 0, 3, 7, 14, 21, 28 after activation | 20 | 0,71 | 10 s/1 min 40 s | Day 0, 3, 7, 14, 21, 28 after activation |
Heravi [10] (2014) | Iran | 20/20 22.1 y 3/17 | Single blinded CCT (Split mouth) | Maxillary canine retraction | Control | Computer measurements on photos of study models | No differences between LG and C after 56 days. | GaAlAs | 810 | 30 s/7 min 30 s | Day 4, 7, 11, 15 and 28 in the first month after Activation, Day 32, 25, 39, 43 and 56 in the second month | – | – | – | – |