Fig. 4

mRNA levels of a RUNX2, b COL-1, c ALP and d OCN for MC3T3-E1 cells seeded on 1) control tissue culture plastic, 2) BCP alone 3) 100 ng rhBMP2, and 4) 100 ng rhBMP2 + BCP at 7 and 14 days post seeding (*p < 0.05, denotes significance between groups, # p < 0.05, denotes significantly lower than all other treatment groups, ** p < 0.05, denotes significantly higher than all other treatment groups)