Table 3 Inflammatory mediator level among women with overall, moderate/severe and without periodontal disease
From: Salivary and serum inflammatory mediators among pre-conception women with periodontal disease
Inflammatory mediator | Women overall periodontal disease (mean ± SD) N = 442 | Women with moderate/severe periodontal disease N = 247 | Women without periodontal disease N = 91 | P *a | P *b |
|---|---|---|---|---|---|
Saliva | |||||
IL-1β (pg/ml) | 92.76 ± 1.16 | 94.63 ± 1.16 | 75.19 ± 1.27 | <0.001 | <0.001 |
β-glucuronidase (U/L) | 699.24 ± 1.22 | 720.54 ± 1.21 | 639.06 ± 1.19 | <0.001 | <0.001 |
TNF-α (pg/ml) | 44.26 ± 1.28 | 45.15 ± 1.02 | 32.46 ± 1.63 | <0.001 | <0.001 |
IL-6 (pg/ml) | 52.46 ± 1.26 | 54.05 ± 1.25 | 43.38 ± 1.26 | <0.001 | <0.001 |
Serum | |||||
IL-1β (pg/ml) | 21.76 ± 2.51 | 21.54 ± 2.66 | 14.59 ± 3.13 | 0.002 | 0.004 |
β-glucuronidase (U/L) | 361.41 ± 1.67 | 368.71 ± 1.70 | 320.54 ± 1.63 | 0.053 | 0.037 |
TNF-α (pg/ml) | 23.34 ± 2.56 | 24.53 ± 2.51 | 15.18 ± 3.94 | 0.005 | 0.003 |
IL-6 (pg/ml) | 18.92 ± 1.97 | 18.73 ± 2.01 | 16.12 ± 2.18 | 0.052 | 0.092 |