Salivary and serum inflammatory mediators among pre-conception women with periodontal disease

BMC Oral Health

Table 5 Linear trend of severity of periodontal disease (none, mild, moderate/severe) with levels of inflammatory mediators in multivariable linear regression^a

Saliva	Slope (95% CI)	P	Serum	Slope (95% CI)	P
IL-1β (pg/ml)	0.099 (0.079, 0.118)	<0.001	IL-1β (pg/ml)	0.160 (0.050, 0.269)	0.004
β-glucuronidase (U/L)	0.059 (0.036, 0.081)	<0.001	β-glucuronidase (U/L)	0.068 (0.011, 0.126)	0.020
TNF-α (pg/ml)	0.152 (0.117, 0.186)	<0.001	TNF-α (pg/ml)	0.216 (0.099, 0.332)	<0.001
IL-6 (pg/ml)	0.097 (0.071, 0.123)	<0.001	IL-6 (pg/ml)	0.063 (−0.016, 0.141)	0.068

^aMultivariable linear regression adjusted for women’s age, educational level, employment status, monthly family income, parity, family periodontal disease history, oral health insurance, BMI, stress score, Oral hygiene. All inflammatory mediators were log-transformed

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