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Fig. 4 | BMC Oral Health

Fig. 4

From: PDGFRβ+/c-kit+ pulp cells are odontoblastic progenitors capable of producing dentin-like structure in vitro and in vivo

Fig. 4

Differentiation of PDGFRβ+/c-kit+ pulp cells under various concentrations of growth factors. a 0–1000 ng/ml of BMP2 treatment. Expressions of DMP1, OCN, and ALP were up-regulated by BMP2 in a concentration-dependent manner. DSPP was up-regulated by 1 ng/ml BMP2. * denotes p < 0.05 compared with 0 ng/ml BMP2. b 0–1000 ng/ml of PDGF-BB treatment. Expression of OCN was down-regulated by PDGF-BB in a concentration-dependent manner. DMP1 and DSPP were inhibited in a non-concentration dependent manner. The effects on ALP were varied. * denotes p < 0.05 compared with 0 ng/ml PDGF-BB

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BMC Oral Health

ISSN: 1472-6831

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