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Fig. 4 | BMC Oral Health

Fig. 4

From: The effect of chlormadinone acetate on odontogenic differentiation of human dental pulp cells: in vitro study

Fig. 4

The signaling pathway of CMA-stimulated odontogenic differentiation in hDPCs, as determined by Western blot analysis and ALP staining. a Phosphorylation of ERK increased within 10 min and gradually decreased in a time-dependent manner. b ERK phosphorylation-dependent CMA expression was suppressed in a dose-dependent manner with U0126, an ERK inhibitor. c 10 uM U0126 significantly decreased CMA-induced odontogenesis. d Quantification of ALP staining by densitometry. *Significant differences compared with the control (p < .05)

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BMC Oral Health

ISSN: 1472-6831

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