Table 2 Allele and genotype frequencies of four VDR gene polymorphisms in 4 ~ 7 years old children
VDR Gene Polymorphisms | Caries experience | Caries-free | p value | OR (95% CI) | |
|---|---|---|---|---|---|
(rs number) | (n = 249) | (n = 131) | |||
BsmI (rs1544410) | BB | 0 | 0 | 0.005 | 1.854 (1.209–2.844) |
Bb | 152 (61.0%) | 60 (45.8%) | |||
bb | 97 (39.0%) | 71 (54.2%) | |||
B | 152 (30.5%) | 60 (22.9%) | 0.027 | 1.479 (1.047–2.090) | |
b | 346 (69.5%) | 202 (77.1%) | |||
TaqI (rs731236) | TT | 230 (92.4%) | 120 (91.6%) | 0.842 | 1.110 (0.511–2.408) |
Tt | 19 (7.6%) | 11 (8.4%) | |||
tt | 0 | 0 | |||
T | 479 (96.2%) | 251 (95.8%) | 0.845 | 1.105 (0.518–2.358) | |
t | 19 (3.8%) | 11 (4.2%) | |||
ApaI (rs7975232) | AA | 44 (17.7%) | 18 (13.1%) | 0.459 | |
Aa | 87 (34.9%) | 43 (33.1%) | |||
aa | 118 (47.4%) | 70 (53.8%) | |||
A | 175 (35.1%) | 79 (30.2%) | 0.17 | 1.255 (0.910–1.731) | |
a | 323 (64.9%) | 183 (69.8%) | |||
FokI (rs10735810) | FF | 69 (27.7%) | 34 (26.0%) | 0.320 | |
Ff | 132 (53.0%) | 63 (48.0%) | |||
ff | 48 (19.3%) | 34 (26.0%) | |||
F | 270 (54.2%) | 131 (50.0%) | 0.285 | 1.184 (0.878–1.598) | |
f | 228 (35.8%) | 131 (50.0%) | |||