Study | Study design | Population | Intervention | Surgical guide | Primary outcomes | Secondary outcomes |
Vercruyssen et al. 2014 [13] | RCT, 1y F/U | 59 patients (72 fully edentulous jaws) | 60 jaws divided in 5 groups (each one n = 12), treated with 5 different surgical template, 4–6 implants for each jaw | 2 groups bone-supported stereolithographic templates, 2 groups mucosa-supported templates, 1 group pilot-drill template | Prosthesis failure, implant failure, biological or prosthetic complications | Peri-implant marginal bone loss, clinical implant evaluation (BOP, paque, pockets), patient’s quality of life improvement |
Pozzi et al. 2014 [14] | RCT, multicentrical, 1y F/U | 51 patients, fully or partially edentulous jaws (some post-extractive placement) | 25 patients treated with guided implant surgery | Stereolithographic surgical templates, stabilized with silicon index and 2–3 anchor pins | Prosthesis failure, implant failure, biological or prosthetic complications | Peri-implant marginal bone loss, time and sessions for rehabilitation delivery, complication time, post-surgical pain, swelling, consumption of painkillers and patient satisfaction, additional treatment cost |