The effects of essential oil mouthrinses with or without alcohol on plaque and gingivitis: a randomized controlled clinical study

Table 2 Whole-mouth mean modified gingival index (MGI) at months 1, 3, and 6 (full analysis set)

Mean MGI	MOH(n = 122)	AFM (n = 121)	ACM (n = 122)
Baseline
Mean ± SE	2.438 ± 0.013	2.452 ± 0.013	2.463 ± 0.013
Month 1
Adj. mean ± SE	2.191 ± 0.014	1.832 ± 0.014	1.838 ± 0.014
Difference between treatments (95% CI)		Percent difference (%)	p- value^a
AFM vs MOH	−0.359 (−0.399, −0.319)	−16.4	<0.001
ACM vs MOH	−0.353 (−0.393, −0.313)	−16.1	<0.001
ACM vs AFM	0.006 (−0.034, 0.046)	0.3	0.756
Month 3^b
Adj. mean ± SE	2.257 ± 0.018	1.772 ± 0.018	1.768 ± 0.018
Difference between treatments (95% CI)		Percent difference (%)	p- value
AFM vs MOH	−0.486 (−0.535, −0.437)	−21.5	<0.001
ACM vs MOH	−0.489 (−0.539, −0.440)	−21.7	<0.001
ACM vs AFM	−0.004 (−0.053, 0.045)	−0.2	0.878
Month 6^c
Adj. mean ± SE	2.201 ± 0.018	1.614 ± 0.018	1.581 ± 0.018
Difference between treatments (95% CI)		Percent difference (%)	p- value
AFM vs MOH	−0.587 (−0.637, −0.538)	−26.7	<0.001
ACM vs MOH	−0.620 (−0.670, −0.570)	−28.2	<0.001
ACM vs AFM	−0.033 (−0.083, 0.017)	−2.0	0.198

ACM Alcohol-containing essential oil mouthrinse, AFM Alcohol-free essential oil mouthrinse, CI Confidence interval, MGI Modified gingival index, MO Mechanical oral hygiene, SE Standard error
^ap-values are based on ANCOVA model with term for treatment and baseline value as covariate
^bAt month 3, data for MOH, AFM, and ACM groups were obtained from 119 subjects in each group
^cAt month 6, data for MOH, AFM, and ACM groups were obtained from 118, 116, and 114 subjects, respectively

ISSN: 1472-6831