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Fig. 1 | BMC Oral Health

Fig. 1

From: Do hypoxia and L-mimosine modulate sclerostin and dickkopf-1 production in human dental pulp-derived cells? Insights from monolayer, spheroid and tooth slice cultures

Fig. 1

Viability of dental pulp-derived cells in monolayer, spheroid and tooth slice culture upon exposure to L-mimosine (L-MIM) or hypoxia. Dental pulp-derived cells were cultured in 2D monolayer, 3D spheroid and tooth slice cultures to test viability after treatment with 1 mM L-MIM or hypoxia. Cell viability in monolayer (a, d) and spheroid culture (b, e) was tested by resazurin-based toxicity assays and pulp viability in tooth slices (c, f) was tested by MTT assay. Data are displayed as mean ± standard deviation (black bars) and relative to the normoxic control (white bar). The level of significance was set at p < 0.05. N equalled 6 or higher

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