Table 3 Transversion of amino acids, according to the vicK gene codons
UA159 | Clinical strains | ||||
|---|---|---|---|---|---|
Mutation | Base site | Codon | Amino acid | Codon | Amino acid |
Silent mutations | 27 | CCC | Proline | CCT | Proline |
105 | TAT | Tyrosine | TAC | Tyrosine | |
126 | AAA | Lysine | AAG | Lysine | |
153 | TTG | Leucine | TTA | Leucine | |
162 | GGC | Glycine | GGT | Glycine | |
201 | GAC | Aspartic acid | GAT | Aspartic acid | |
204 | TTG | Leucine | TTA | Leucine | |
255 | ACG | Threonine | ACT | Threonine | |
276 | GAG | Glutamic acid | GAA | Glutamic acid | |
286 | CTG | Leucine | TTG | Leucine | |
324 | TTG | Leucine | TTA | Leucine | |
345 | AAG | Lysine | AAA | Lysine | |
351 | ACC | Threonine | ACT | Threonine | |
360 | AAT | Asparagine | AAC | Asparagine | |
474 | CCA | Proline | CCG | Proline | |
492 | CGG | Arginine | CGA | Arginine | |
645 | GTC | Valine | GTT | Valine | |
667 | TTA | Leucine | CTA | Leucine | |
735 | AGC | Serine | AGT | Serine | |
829 | CTA | Leucine | TTA | Leucine | |
834 | GAT | Aspartic acid | GAC | Aspartic acid | |
918 | AAG | Lysine | AAA | Lysine | |
924 | TAC | Tyrosine | TAT | Tyrosine | |
1056 | ACG | Threonine | ACA | Threonine | |
1062 | CAG | Glutamine | CAA | Glutamine | |
1074 | ACA | Threonine | ACC/ACG | Threonine | |
1083 | ATC | Isoleucine | ATT | Isoleucine | |
1095 | TCC | Serine | TCT | Serine | |
1215 | AAA | Lysine | AAG | Lysine | |
1224 | GTC | Valine | GTT | Valine | |
1269 | GAA | Glutamic acid | GAG | Glutamic acid | |
1305 | AAC | Asparagine | AAT | Asparagine | |
Missense mutations | 173 | GAT | Aspartic acid | GGT | Aspartic acid |
337 | AGC | Serine | CGC | Arginine | |
470 | ACG | Threonine | ATG | Methionine | |
1051 | ATA | Isoleucine | GTA | Valine | |
1132 | CTT | Leucine | TTT | Phenylalanine | |
1258 | GAG | Glutamic acid | AAG | Lysine | |
1260 | GAG | Glutamic acid | GAC | Aspartic acid | |
1227 | ACC | Threonine | ATC | Isoleucine | |
1348 | TCA | Serine | CCA | Proline | |