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Table 5 The distribution frequencies of the missense mutation sites of the vicK gene in the high-severity caries and caries-free groups

From: Relationship between the genetic polymorphisms of vicR and vicK Streptococcus mutans genes and early childhood caries in two-year-old children

Missense

Caries-free (n = 121)

High-severity (n = 121)

x 2

P-valuea

mutation

n (%)

n (%)

173 A → G†

0

0.00

3

2.48

3.308

0.247b

337 A → C

118

97.52

115

95.04

1.309

0.499b

470 C → T

1

0.83

12

9.92

9.836

0.002a

1051 A → G

115

95.04

115

95.04

0

1.000b

1132 C → T

2

1.65

0

0.00

2.017

0.498b

1258 G → A

5

4.13

0

0.00

5.105

0.060b

1260 G → C

3

2.48

0

0.00

3.308

0.247b

1277 C → T

6

4.96

1

0.83

3.678

0.120b

1348 T → C

6

4.96

3

2.48

1.309

0.499b

  1. †A → G, A represents the 23 locus base in UA159, and G represents the 23 locus base in the clinical strains
  2. aChi-square test
  3. bFisher’s exact test