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Table 6 Demographic characteristics and clinical features of oral lichen planus patients and healthy control subjects in the validation portion of this study

From: Putative salivary protein biomarkers for the diagnosis of oral lichen planus: a case-control study

  OLP (n = 24) Healthy control (n = 24) p
Age (years)
 Mean ± SE 57.25 ± 12.41 51.79 ± 11.71 0.124
 Range 30–76 33–70  
Gender
 F/M 20/4 22/2  
Clinical appearance
 R & E 16 (66.7%)   
 R & E (with erosion) 2 (8.3%)   
 R & E & U 6 (25%)   
Site
 Buccal mucosa 6 (24.9%)   
 Buccal mucosa and gingiva 7 (29.05%)   
 Buccal mucosa and tongue 1 (4.15%)   
 Buccal mucosa, labial mucosa and gingiva 1 (4.15%)   
 Buccal mucosa, gingiva and tongue 2 (8.3%)   
 Gingiva 4 (16.6%)   
 Gingiva and palate 1 (4.15%)   
 Palate 1 (4.15%)   
 Palate and labial mucosa 1 (4.15%)   
Salivary C3c median levels (ng/ml) (Q1, Q3) 13.53 (7.87, 27.36) 9.91 (4.60, 16.97)  
Salivary FGD median levels (ng/ml) (Q1, Q3) 9.65 (5.47, 18.76) 9.60 (4.48, 17.77)  
Salivary cystatin SA median levels (ng/ml) (Q1, Q3) 2.95 (1.52, 3.72) 4.12 (1.38, 6.66)  
Salivary C3c log mean ± SD levels (ng/ml) 1.21 ± 0.41 0.95 ± 0.43 0.041
Salivary FGD log mean ± SD levels (ng/ml) 1.01 ± 0.38 0.90 ± 0.47 0.398
Salivary cystatin SA log mean ± SD levels (ng/ml) 0.39 ± 0.23 0.51 ± 0.46 0.279
  1. SD Standard Deviation, R Reticular/hyperkeratotic lesions, E Erosive lesions, U Ulcerative lesions, C3c complement C3c, FGD fibrinogen fragment D, OLP oral lichen planus