Putative salivary protein biomarkers for the diagnosis of oral lichen planus: a case-control study

BMC Oral Health

Table 6 Demographic characteristics and clinical features of oral lichen planus patients and healthy control subjects in the validation portion of this study

	OLP (n = 24)	Healthy control (n = 24)	p
Age (years)
Mean ± SE	57.25 ± 12.41	51.79 ± 11.71	0.124
Range	30–76	33–70
Gender
F/M	20/4	22/2
Clinical appearance
R & E	16 (66.7%)
R & E (with erosion)	2 (8.3%)
R & E & U	6 (25%)
Site
Buccal mucosa	6 (24.9%)
Buccal mucosa and gingiva	7 (29.05%)
Buccal mucosa and tongue	1 (4.15%)
Buccal mucosa, labial mucosa and gingiva	1 (4.15%)
Buccal mucosa, gingiva and tongue	2 (8.3%)
Gingiva	4 (16.6%)
Gingiva and palate	1 (4.15%)
Palate	1 (4.15%)
Palate and labial mucosa	1 (4.15%)
Salivary C3c median levels (ng/ml) (Q1, Q3)	13.53 (7.87, 27.36)	9.91 (4.60, 16.97)
Salivary FGD median levels (ng/ml) (Q1, Q3)	9.65 (5.47, 18.76)	9.60 (4.48, 17.77)
Salivary cystatin SA median levels (ng/ml) (Q1, Q3)	2.95 (1.52, 3.72)	4.12 (1.38, 6.66)
Salivary C3c log mean ± SD levels (ng/ml)	1.21 ± 0.41	0.95 ± 0.43	0.041
Salivary FGD log mean ± SD levels (ng/ml)	1.01 ± 0.38	0.90 ± 0.47	0.398
Salivary cystatin SA log mean ± SD levels (ng/ml)	0.39 ± 0.23	0.51 ± 0.46	0.279

SD Standard Deviation, R Reticular/hyperkeratotic lesions, E Erosive lesions, U Ulcerative lesions, C3c complement C3c, FGD fibrinogen fragment D, OLP oral lichen planus

ISSN: 1472-6831