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Table 3 Category of evidence and strength of recommendation

From: Consequences of early extraction of compromised first permanent molar: a systematic review

Topic Recommendation Category of evidence Strength of recommendation
Effects on post extraction space Early extraction of compromised FPM leads to decrease in post extraction space III*** C^
Effect on development and eruption of SPM Early extraction of compromised FPM results in accelerated development and eruption of SPM III*** C^
Effect on development and eruption of third molar Early extraction of compromised FPM results in accelerated development and eruption of third molar III*** C^
Caries and/or filling of adjacent teeth Early extraction of compromised FPM causes a decrease in caries and/or fillings of proximal surfaces on adjacent teeth III*** C^
Effects on incisors Early extraction of compromised FPM results in lingual tipping and retrusion of lower incisors III*** C^
Effects on skeletal development Early extraction of compromised FPM results in counterclockwise rotation of the occlusal plane III*** C^
  1. Notes: ***According to the system devised by Shekelle et al. [13] to grade evidence, Category III is evidence from nonexperimental descriptive studies, such as comparative studies, correlation studies, cohort studies, and case-control studies. ^According to the system used for classifying the strength of the recommendations devised by Shekelle et al. [13], Class C is directly based on category III evidence or a recommendation extrapolated from category I or II evidence
  2. Abbreviations: FPM first permanent molar, SPM second permanent molar
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