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Table 2 Levels of ferritin, hepcidin and hepcidin/ferritin in serum and saliva

From: Serum and salivary ferritin and Hepcidin levels in patients with chronic periodontitis and type 2 diabetes mellitus

  Control CP T2DM CP + T2DM P-value
Serum ferritin (ng/ml, Median (IQR)) 196.2 (106.6, 241.6) 265.1 (166.1, 358.5) 196.3 (88.8, 369.6) 197.7 (128.9, 366.6) P1 = 0.008a*
P2 = 0.015a* P3 = 0.036a*
log serum ferritin (Mean ± SD) 2.20 ± 0.32 2.42 ± 0.20 2.23 ± 0.40 2.38 ± 0.31
Serum hepcidin (ng/ml, Mean ± SD) 179.37 ± 79.86 249.56 ± 77.15 197.92 ± 103.04 218.36 ± 94.05 P1 = 0.003a*
P2 = 0.036a* P3 = 0.040a*
Serum hepcidin/ferritin (Mean ± SD) 1.00 ± 0.18 0.95 ± 0.26 1.00 ± 0.31 0.88 ± 0.24 P2 = 0.007a* P4 = 0.015a*
Salivary ferritin (ng/ml, Median (IQR)) 6.50 (5.49, 9.56) 16.74 (8.44, 23.93) 12.61 (7.47, 26.16) 12.81 (7.42, 18.13) P1 = 0.008a*
P5 = 0.014a*
log salivary ferritin (Mean ± SD) 0.83 ± 0.32 1.14 ± 0.36 1.11 ± 0.46 1.06 ± 0.30
Salivary hepcidin (ng/ml, Median (IQR)) 1.12 (0.89, 1.73) 1.64 (0.93, 3.19) 1.79 (0.93, 5.14) 1.54 (0.99, 3.80) P = 0.307a
1/(salivary hepcidin) (Mean ± SD) 0.84 ± 0.38 0.66 ± 0.44 0.62 ± 0.44 0.63 ± 0.36
Salivary hepcidin/ferritin
(Median (IQR))
0.17 (0.12, 0.37) 0.11 (0.08, 0.34) 0.18 (0.90, 0.39) 0.13 (0.92, 0.34) P = 0.939a
log (salivary hepcidin/ferritin) (Mean ± SD) −0.69 ± 0.34 − 0.77 ± 0.51 −0.72 ± 0.42 − 0.77 ± 0.38
  1. P1: Control vs CP; P2: Control vs T2DM + CP; P3: CP vs T2DM; P4: T2DM vs T2DM + CP; P5: Control vs T2DM
  2. aAnalysis of covariance (ANCOVA)
  3. *Significantly different P < 0.05