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Table 1 Clinical and radiographic findings of teeth receiving RET with BC or PRF as scaffold at 1-year Follow-up

From: The efficacy of platelet-rich fibrin as a scaffold in regenerative endodontic treatment: a retrospective controlled cohort study

Procedure performed Preoperative variables Postoperative variables at 1-year follow-up
      Radiographic findings Sign and symptom Sensitivity test
  Tooth# (age/sex) Aetiology Pulp/periapical conditions Foramina development (Nolla’s stage) Periapical healing Apex closure Root elongation Dentinal wall thickening Resolution EPT/Cold test (time)
RET with a BC (average age = 11.6 y) 45 (10 y/F) DE AP 8 Yes Yes Yes Yes Yes +(6 m)
  45 (12 y/M) DE AP 8 Yes Yes Yes Yes Yes
  45 (12 y/F) DE AP 8 Yes Yes Yes Yes Yes
  45 (12 y/F) DE AP 8 Yes Yes Yes Yes Yes
  11 (12 y/M) Tooth fracture AP 8 Yes No No No Yes
RET with PRF (average age = 11.4 y) 35 (10 y/M) DE AP 8 Yes Yes Yes Yes Yes
  45 (12 y/F) DE AP 8 Yes Yes Yes Yes Yes + (6 m)
  35 (12 y/M) DE AP 8 Yes Yes Yes Yes Yes + (9 m)
  45 (14 y/F) DE AP 8 Yes No No No Yes
  21 (9 y/M) Tooth fracture AP 8 Yes Yes Yes Yes Yes + (9 m)
  1. RET regenerative endodontic treatment, BC blood clot, PRF platelet-rich fibrin, F female, M male, DE dens evaginatus, AP apical periodontitis; +, positive; −, negative