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Table 1 Characteristics of included studies

From: A comparison of treatment effectiveness between clear aligner and fixed appliance therapies

Author (Year)

Country

Study design

Clinicians

Inclusion criteria

Patients number (male/female)

Mean age

Intervention

Comparison

Aligner

Brace

Aligner

Brace

Djeu (2005) [10]

America

Retrospective cohort study

Certified orthodontists

Nonextraction patients. Two groups had similar discrepancy index scores before treatment.

48 (UK)

48 (UK)

33.6 ± 11.8

23.7 ± 11.0

Invisalign®

Tip-edge braces

Kuncio (2007) [13]

America

Retrospective cohort study

Certified orthodontists

Nonextraction patients. Two groups had similar distributions of gender, ethnicity, age, retainer wear, treatment, and posttreatment length.

11 (1/10)

11 (1/10)

33.97± 8.98

26.79 ± 12.12

Invisalign®

Tip-edge braces

Pavoni (2011) [15]

Italy

Prospective cohort study

Orthodontists

Nonextraction patients. Class I malocclusion; mild crowding; vertebral maturation.

20 (8/12)

20 (11/9)

18.33

15.50

Invisalign®

Self-ligation braces

Li (2015) [17]

China

Randomized controlled trial

Orthodontists

Extraction patients. Class I malocclusion; severity in complexity with discrepancy index score of 25.

76 (27/45)

76 (27/45)

35.2±7.3

32.2 ± 8.3

Invisalign®

3 M Unitek braces

Grunheid [14]

America

Retrospective cohort study

Orthodontic specialists

Nonextraction patients. Class I malocclusion; no periodontal attachment loss.

30 (8/22)

30 (8/22)

25.0± 11.8

26.3 ± 13.5

Invisalign®

Preadjusted edgewise braces

Hennessy (2016) [16]

Ireland

Randomized controlled trial

Postgraduate students

Nonextraction patients. Mild crowding; skeletal class I malocclusion.

20 (6/14)

20 (7/13)

29.1± 7.5

23.7 ± 7.0

Invisalign®

Preadjusted edgewise braces

Gu (2017) [12]

America

Retrospective cohort study

Orthodontic faculty and residents

Nonextraction patients.

48 (16/32)

48 (18/30)

26.0± 9.7

22.1 ± 7.9

Invisalign®

Straight-wire edgewise braces

Lanteri (2018) [11]

Italy

Retrospective cohort study

UK

Nonextraction patients. Two groups had similar dental crowding and PAR index scores before treatment.

100 (30/70)

100 (30/70)

28± 10

25± 10

Invisalign®

Straight-wire edgewise braces (MBT prescription)

  1. PAR Peer Assessment Rating; UK Unknown