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Fig. 4 | BMC Oral Health

Fig. 4

From: WIF1 enhanced dentinogenic differentiation in stem cells from apical papilla

Fig. 4

Overexpression of WIF1 enhanced dentinogenesis in SCAPs. SCAPs were transplanted subcutaneously into immunocompromised mice and monitored for 8 weeks. (a) H&E-stained micrographs showing bone/dentin-like tissue formation. (b) Qualitative measurement of bone/dentin-like tissues in tissue samples. (c) Immunohistochemical results demonstrating DSPP expression. (d) Immunohistochemical results showing negative control staining in the absence of primary antibody. All error bars represent the s.d. (n = 5). Bar: 100 μm. **P ≤ 0.05. B/D, bone/dentin-like tissues; HA, hydroxyapatite tricalcium carrier

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