Table 3 Intent-to-treat (ITT) analysis: primary and secondary outcomes between the personalised and non-personalised groups
ITT analysis | Group | |||
|---|---|---|---|---|
Personalised (n = 56) | Non-personalised (n = 55) | p value | ||
Primary outcome (‘chance of avoiding new cavities’) | Mean difference (95% CI) | |||
Baseline | ||||
mean (SD) | 39.3 (20.2) | 36.5 (23.4) | ||
median (min. to max.) | 37.5 (6 to 81) | 31.0 (3 to 94) | ||
Follow-up | 0.7 (−5.5, 6.9) | p = 0.820 | ||
mean (SD) | 46.2 (19.6) | 42.8 (22.0) | ||
median (min. to max.) | 44.5 (8 to 83) | 41.0 (9 to 93) | ||
Secondary outcome (number (%) of participants with Score 0, 1) | Odds ratio (95% CI) | |||
‘Diet frequency’ | ||||
Baseline | 39 (69.6) | 36 (65.5) | ||
Follow-up | 47 (83.9) | 43 (78.2) | 0.8 (0.3, 2.3) | p = 0.663 |
‘Diet contents’ | ||||
Baseline | 27 (48.2) | 30 (54.5) | ||
Follow-up | 27 (48.2) | 30 (54.5) | 1.0 (0.4, 2.6) | p = 0.945 |
‘Plaque amount’ | ||||
Baseline | 25 (44.6) | 19 (34.5) | ||
Follow-up | 31 (55.4) | 33 (60.0) | 1.7 (0.7, 3.9) | p = 0.247 |
‘Mutans streptococci’ | ||||
Baseline | 34 (60.7) | 24 (43.6) | ||
Follow-up | 36 (64.3) | 31 (56.4) | 1.1 (0.4, 2.6) | p = 0.917 |
‘Fluoride programme’a | ||||
Baseline | 55 (98.2) | 51 (92.7) | ||
Follow-up | 56 (100.0) | 54 (98.2) | p = 0.941 | |
‘Saliva secretion’ | ||||
Baseline | 45 (80.4) | 40 (72.7) | ||
Follow-up | 51 (91.1) | 41 (74.5) | 0.3 (0.1, 0.9) | p = 0.036* |
‘Saliva buffer capacity’ | ||||
Baseline | 54 (96.4) | 51 (92.7) | ||
Follow-up | 45 (80.4) | 40 (72.7) | 0.8 (0.3, 2.1) | p = 0.653 |