Table 4 Per-protocol analysis: primary and secondary outcomes between the personalised and non-personalised groups
Per-protocol analysis | Group | |||
|---|---|---|---|---|
Personalised (n = 21) | Non-personalised (n = 33) | Mean difference (95% CI) | p value | |
Primary outcome (‘chance of avoiding new cavities’) | ||||
Baseline | ||||
mean (SD) | 36.7 (18.6) | 29.4 (20.6) | ||
median (min. to max.) | 37 (11 to 67) | 26 (3 to 83) | ||
Follow-up | 4.0 (−5.6, 13.5) | p = 0.410 | ||
mean (SD) | 44.6 (18.4) | 35.0 (20.6) | ||
median (min. to max.) | 39 (16 to 83) | 32 (9 to 84) | ||
Secondary outcome (number (%) of participants with Score 0, 1)a | ||||
‘Diet frequency’ | ||||
Baseline | 12 (57.1) | 21 (63.6) | ||
Follow-up | 18 (85.7) | 25 (75.8) | ||
‘Diet contents’ | ||||
Baseline | 10 (47.6) | 14 (42.4) | ||
Follow-up | 8 (38.1) | 13 (39.4) | ||
‘Plaque amount’ | ||||
Baseline | 8 (38.1) | 9 (27.3) | ||
Follow-up | 12 (57.1) | 18 (54.5) | ||
‘Mutans streptococci’ | ||||
Baseline | 9 (42.9) | 8 (24.2) | ||
Follow-up | 12 (57.1) | 12 (36.4) | ||
‘Fluoride programme’ | ||||
Baseline | 21 (100.0) | 30 (90.9) | ||
Follow-up | 21 (100.0) | 32 (97.0) | ||
‘Saliva secretion’ | ||||
Baseline | 20 (95.2) | 23 (69.7) | ||
Follow-up | 21 (100.0) | 24 (72.7) | ||
‘Saliva buffer capacity’ | ||||
Baseline | 21 (100.0) | 31 (93.9) | ||
Follow-up | 18 (85.7) | 27 (81.8) | ||