Table 2 Common upregulated DEGs (p < 0.05, FC > 2) in chronic periodontitis
Gene Symbol | Gene Description | Probe |
|---|---|---|
ARHGAP9 | pho GTPase activating protein 9 | 224451_x_at |
ATP2A3 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 | 207522_s_at |
BHLHA15 | basic helix-loop-helix family member A15 | 235965_at |
C3 | complement component 3 | 217767_at |
CCL18 | C-C motif chemokine ligand 18 | 209924_at |
CD19 | CD19 molecule | 206398_s_at |
CD53 | CD53 molecule | 203416_at |
CD79A | CD79a molecule | 1555779_a_at |
CECR1 | adenosine deaminase 2 | 219505_at |
CHST2 | carbohydrate sulfotransferase 2 | 203921_at |
CLDN10 | claudin 10 | 205328_at |
COL15A1 | collagen type XV alpha 1 | 203477_at |
COL4A1 | collagen type IV alpha 1 | 211981_at |
COL4A2 | collagen type IV alpha 2 | 211964_at |
CSF2RB | colony stimulating factor 2 receptor beta | 205159_at |
CSF3 | colony stimulating factor 3 | 207442_at |
CXCL12 | chemokine (C-X-C motif) ligand 12 | 203666_at |
CXCL8 | chemokine (C-X-C motif) ligand 8 | 202859_x_at |
CYTIP | cytohesin 1 interacting protein | 209606_at |
DENND5B | DENN domain containing 5B | 228551_at |
DERL3 | derlin 3 | 229721_x_at |
EAF2 | ELL associated factor 2 | 219551_at |
ENPP2 | ectonucleotide pyrophosphatase phosphodiesterase 2 | 209392_at, 210839_s_at |
ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 207691_x_at, 209474_s_at |
EVI2B | ecotropic viral integration site 2B | 211742_s_at |
FABP4 | fatty acid binding protein 4 | 203980_at |
FAM30A | family with sequence similarity 30 member A | 206478_at |
FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 210889_s_at |
FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 204007_at |
FCN1 | ficolin 1 | 205237_at |
FCRL5 | Fc receptor like 5 | 224405_at |
FCRLA | Fc receptor like A | 235372_at |
FKBP11 | FKBP prolyl isomerase 11 | 219117_s_at |
FPR1 | formyl peptide receptor 1 | 205119_s_at |
HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 202957_at |
ICAM2 | intercellular adhesion molecule 2 | 213620_s_at, 204683_at |
ICAM3 | intercellular adhesion molecule 3 | 204949_at |
IGHM | immunoglobulin heavy constant mu | 209374_s_at |
IGKC | immunoglobulin kappa constant | 216207_x_at, 215217_at |
IGKV1OR2–118 | immunoglobulin kappa variable 1/OR2–118 | 217480_x_at |
IGLC1 | immunoglobulin lambda constant 1 | 211655_at |
IGLJ3 | immunoglobulin lambda joining 3 | 216853_x_at |
IGLL5 | immunoglobulin lambda like polypeptide 5 | 217235_x_at |
IGLV1–44 | immunoglobulin lambda variable 1–44 | 216430_x_at, 216573_at |
IKZF1 | IKAROS family zinc finger 1 | 227346_at |
IL10RA | interleukin 10 receptor, alpha | 204912_at |
IL1B | interleukin 1 beta | 205067_at |
IL2RG | interleukin 2 receptor subunit gamma | 204116_at |
IRF4 | interferon regulator factor 4 | 204562_at |
ITGAL | integrin subunit alpha L | 1554240_a_at |
ITM2C | integral membrane protein 2C | 221004_s_at |
JCHAIN | joining chain of multimeric IgA and IgM | 212592_at |
KLHL6 | kelch like family member 6 | 228167_at |
LAX1 | lymphocyte transmembrane adaptor 1 | 207734_at |
MME | membrane metalloendopeptidase | 203434_s_at |
MMP7 | metallopeptidase 7 | 204259_at |
MS4A1 | 4-domains A1 | 228592_at |
NEDD9 | neural precursor cell expressed developmentally down regulated 9 | 1560706_at |
P2RY8 | P2Y receptor family member 8 | 229686_at |
PECAM1 | adhesion molecule 1 | 208981_at, 208982_at, 208983_s_at |
PIM2 | pim-2 proto-oncogene serine/threonine inase | 204269_at |
PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase type 1 beta | 205632_s_at |
PLPP5 | phospholipid phosphatase 5 | 226150_at |
PROK2 | prokineticine | 232629_at |
RAB30 | RAB30, member RAS oncogene family | 228003_at |
RAC2 | Rac family small GTPase 2 | 213603_s_at |
RGS1 | Regulator of G protein signaling 1 | 216834_at |
SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 220330_s_at |
SEL1L3 | SEL1L family member 3 | 212314_at |
SELL | selectin L | 204563_at |
SELM | selenoprotein M | 226051_at |
SLAMF7 | SLAM family member 7 | 219159_s_at, 234306_s_at |
SPAG4 | sperm associated antigen 4 | 219888_at |
SRGN | serglycin | 201858_s_at, 201859_at |
ST6GAL1 | ST6 beta-galactoside alpha-2, 6-sialyltransferase 1 | 201998_at |
STAP1 | signal transducing adaptor family member 1 | 220059_at |
TAGAP | T cell activation RhoGTPase activating protein | 229723_at, 242388_x_at, 1552542_s_at, 234050_at |
TAGLN | transgelin | 205547_s_at |
THEMIS2 | thymocyte selection associated family member 2 | 210785_s_at |
TNFRSF17 | TNF superfamily member 17 | 206641_at |
ZBP1 | Z-DNA binding protein 1 | 242020_s_at |