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Table 3 Common downregulated DEGs (p < 0.05, FC < −2) in chronic periodontitis

From: Investigation of molecular biomarker candidates for diagnosis and prognosis of chronic periodontitis by bioinformatics analysis of pooled microarray gene expression datasets in Gene Expression Omnibus (GEO)

Gene Symbol

Gene Description

Probe

AADAC

arylacetamide deacetylase

205969_at

AADACL2

arylacetamide deacetylase like 2

240420_at

ABCA12

ATP binding cassette subfamily A member 12

215465_at

AHNAK2

AHNAK nucleoprotein 2

1558378_a_at

ARG1

arginase 1

206177_s_at

ATP6V1C2

ATPase H+ transporting V1 subunit C2

1552532_a_at

BPIFC

BPI fold containing family C

1555773_at

CALML5

calmodulin like 5

220414_at

CLDN20

claudin 20

1554812_at

CWH43

cell wall biogenesis 43 C-terminal homolog

220724_at

CYP2C18

cytochrome P450 family 2 subfamily C member 18

215103_at

CYP3A5

cytochrome P450 family 3 subfamily A member 5

205765_at

DSC1

desmocollin 1

207324_s_at

DSC2

desmocollin 2

204750_s_at

ELOVL4

ELOVL fatty acid elongase 4

219532_at

EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

220161_s_at

EXPH5

exophilin 5

213929_at, 214734_at

FLG

filaggrin

215704_at

FLG2

filaggrin family member 2

1569410_at

FOXN1

forkhead box N1

1558687_a_at

FOXP2

forkhead box P2

1555647_a_at, 235201_at, 1555516_at

GJA3

gap junction protein alpha 3

239572_at

KRT10

keratin 10

207023_x_at

LGALSL

galectin like

226188_at

LOR

loricrin

207720_at

LY6G6C

lymphocyte antigen 6 family member G6C

207114_at

MAP 2

microtubule associated protein 2

225540_at

MUC15

mucin 15, cell surface associated

227241_at, 227238_at

NEFL

neurofilament light

221916_at, 221805_at

NEFM

neurofilament medium

205113_at

NOS1

nitric oxide synthase 1

239132_at

NPR3

natriuretic peptide receptor 3

219789_at

NSG1

neuronal vesicle trafficking associated 1

209570_s_at

POF1B

POF1B actin binding protein

219756_s_at, 1555383_a_at

PTGER3

prostaglandin E receptor 3

213933_at

RORA

RAR related orphan receptor A

210426_x_at, 210479_s_at, 235567_at, 226682_at

RPTN

repetin

1553454_at

SH3GL3

SH3 domain containing GRB2 like 3, endophilin A3

205637_s_at

SLC16A9

solute carrier family 16 member 9

227506_at

SPAG17

sperm associated antigen 17

233516_s_at

WASL

Wiskott-Aldrich syndrome like

205809_s_at

YOD1

YOD1 deubiquitinase

227309_at