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Table 3 Results of the multivariate meta-analysis

From: Disease severity, debridement approach and timing of drug modify outcomes of adjunctive azithromycin in non-surgical management of chronic periodontitis: a multivariate meta-analysis

Interacrtions in the full model = Outcome*Baseline Value, Outcome*S/RSD Type, Outcome*Timing

Parameter

Estimated SMD

P value

95% C.I

Outcome: CAL

0.17

0.76

-0.92-1.26

Outcome: PPD

1.17

0.01

0.27–2.07*

Baseline Value

0.01

0.87

−0.10-0.12

S/RSD Type: PMD (reference value = FMD)

0.22

0.50

−0.42-0.86

Timing: Pre-therapy (reference value = Post-Therapy)

0.13

0.72

−0.57-0.83

PPD*Baseline

0.11

< 0.01

0.08–0.15***

PPD*S/RSD Type PMD

−1.25

< 0.01

−1.73--0.78***

PPD*Timing: Pre-therapy

−1.18

< 0.01

−1.48--0.87***

Model Statistics

Log Likelihood ratio

Deviance

AIC

BIC

−38.06

76.13

94.20

99.88

Variance Components: Study, number of levels = 09, Estimated 휎2 value: 0.10

Test for Residual Heterogeneity, Moderators and Model Comparison

Test for Residual Heterogeneity: QE (df = 14) = 88.50, p -value < 0.01

Test of Moderators: QM (df = 8) = 150.03, p-value < 0.01

Model comparsion with null model without moderators (ANOVA)

 

AIC

Log Likelihood ratio

Likelihood Ratio Test Statistic

P value

Model QE

Full model (df = 9)

94.20

−38.06

  

88.50

Reduced (df = 3)

185.23

−89.54

103.10

< 0.01

201.50

  1. *p < 0.05, **p < 0.01, *** p < 0.0001, Significant values in bold font