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Table 3 Evaluation of NBI pattern III-IV and pattern IV alone as a diagnostic test for OSCC/Cis/HGD, with and without OLP patients

From: Oral lichen planus and other confounding factors in narrow band imaging (NBI) during routine inspection of oral cavity for early detection of oral squamous cell carcinoma: a retrospective pilot study

Diagnostic test

Pattern III-IV (95% CI)

Pattern IV (95% CI)

Sensitivity

 With OLP patients

96.2% (80.4–99.9%)

84.6% (65.1–95.6%

 Without OLP patients

96.2% (80.4–99.9%)

84.6% (65.1 95.6%)

Specificity

 With OLP patients

71.3% (60.0–80.8%)

97.5% (91.2–99.7%)

 Without OLP patients

80.0% (66.3–89.9%)

96.0% (86.3–99.5%)

PLR

 With OLP patients

3.34 (2.35–4.76)

33.85 (8.53–134.30)

 Without OLP patients

4.81 (2.75–8.41)

21.15 (5.39–83.06)

NLR

 With OLP patients

0.05 (0.01–0.37)

0.16 (0.06–0.39)

 Without OLP patients

0.05 (0.01–0.33)

0.16 (0.06–0.40)

PPV

 With OLP patients

52.1% (43.3–60.7%)

91.7% (73.5–97.7%

 Without OLP patients

71.4% (58.8–81.4%)

91.7% (73.7–97.7%)

NPV

 With OLP patients

98.3% (89.2–99.7%

95.1% (88.8–97.9%

 Without OLP patients

97.6% (85.3–99.6%)

92.3% (82.9–96.7%)

Accuracy

 With OLP patients

77.4% (68.2–84.9%)

94.3% (88.1–97.9%)

 Without OLP patients

85.5% (75.6–92.5%)

92.1% (83.6–97.1%)

  1. PLR positive likelihood ratio, NLR negative likelihood ratio, PPV positive predictive value, NPV negative predictive value, CI confidence interval