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Table 3 Evaluation of NBI pattern III-IV and pattern IV alone as a diagnostic test for OSCC/Cis/HGD, with and without OLP patients

From: Oral lichen planus and other confounding factors in narrow band imaging (NBI) during routine inspection of oral cavity for early detection of oral squamous cell carcinoma: a retrospective pilot study

Diagnostic test Pattern III-IV (95% CI) Pattern IV (95% CI)
Sensitivity
 With OLP patients 96.2% (80.4–99.9%) 84.6% (65.1–95.6%
 Without OLP patients 96.2% (80.4–99.9%) 84.6% (65.1 95.6%)
Specificity
 With OLP patients 71.3% (60.0–80.8%) 97.5% (91.2–99.7%)
 Without OLP patients 80.0% (66.3–89.9%) 96.0% (86.3–99.5%)
PLR
 With OLP patients 3.34 (2.35–4.76) 33.85 (8.53–134.30)
 Without OLP patients 4.81 (2.75–8.41) 21.15 (5.39–83.06)
NLR
 With OLP patients 0.05 (0.01–0.37) 0.16 (0.06–0.39)
 Without OLP patients 0.05 (0.01–0.33) 0.16 (0.06–0.40)
PPV
 With OLP patients 52.1% (43.3–60.7%) 91.7% (73.5–97.7%
 Without OLP patients 71.4% (58.8–81.4%) 91.7% (73.7–97.7%)
NPV
 With OLP patients 98.3% (89.2–99.7% 95.1% (88.8–97.9%
 Without OLP patients 97.6% (85.3–99.6%) 92.3% (82.9–96.7%)
Accuracy
 With OLP patients 77.4% (68.2–84.9%) 94.3% (88.1–97.9%)
 Without OLP patients 85.5% (75.6–92.5%) 92.1% (83.6–97.1%)
  1. PLR positive likelihood ratio, NLR negative likelihood ratio, PPV positive predictive value, NPV negative predictive value, CI confidence interval