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Table 5 Population characteristics

From: Early wound healing outcomes after regenerative periodontal surgery with enamel matrix derivatives or guided tissue regeneration: a systematic review

Author, year of publication

Patient’s characteristics

Teeth and defect characteristics at baseline

Number of patients

Gender (m/f)

Mean age/ Range (years)

Type of periodontitis

Drop-out

Number/Type of tooth

Number/Type of defects

A.Sculean et al. 1999a [56]

16

10 m/6f

NA

NA

chronic periodontitisa

0

32

NA

32

2 to 3-wall intrabony defects

A.Sculean et al. 1999b [60]

14

NA

NA

NA

chronic periodontitis

0

14

teeth scheduled for extraction

14

advanced intrabony defects

(teeth scheduled for extraction)

N. Donos et al. 2004 [62]

9

NA

NA

40–73

chronic periodontitis

0

14 (EMD 4; GTR 3; EMD + GTR 7)

mandibular molars

14

degree III furcation-involved defects

P. Cortellini et al. 2005 [57]

40

17 m/23f

41.3 ± 10.7

NA

chronic periodontitis

0

40

(e-PTFE TrM 12;

BM + BG 11;

BM 7;

EMD 10)

NA

40

intrabony defects

1-wall

1-wall

2 to 3-wall

3-wall

A. Crea et al. 2008 [61]

40

19 m/21f

45.8

35–66

chronic periodontitis

1

40 (39 evaluable) anterior/posterior

40 (39 evaluable) 3-wall intrabony defects

V. Iorio-Siciliano et al. 2011 [58]

40

19 m/21f

NA

39–52

chronic periodontitis

0

40

single-rooted teeth

40

non- contained intrabony defects combination

≥80% 1-wall component (2 to 3-wall component in the most apical part)

V. Iorio-Siciliano et al. 2014 [59]

40

18 m/22f

44.4

33–57

chronic periodontitis

0

40

single- and multi-rooted teeth

40

non- contained intrabony defects

combination

≥70% 1-wall component (2 to 3-wall component in the most apical part)

  1. BG bone graft, BM bioabsorbable membrane, EMD enamel matrix derivative, e-PTFE expanded polytetrafluoroethylene, f female, GTR guided tissue regeneration, m male, NA not available, PD probing depth, TrM titanium reinforced membrane
  2. aconfirmed by the author (A.S)