Table 4 Bias assessment of the included mouse animal model experiments
Author and publication year | Sample-size calculation | Randomization of treatment or control | Allocation concealment | Blinded assessment of outcome | Suitable animal model | Avoidance of anaesthetics with marked intrinsic properties | Statement of control of temperature | Statement of compliance with regulatory requirements | Publication in peer-reviewed journal | Statement regarding possible conflict of interest |
|---|---|---|---|---|---|---|---|---|---|---|
Matsubara et al., 2012 [33] | – | ✓ | – | – | ✓ | – | – | ✓ | ✓ | – |
Ishijima et al., 2012 [34] | – | ✓ | – | – | ✓ | ✓ | ✓ | ✓ | ✓ | – |
Elahi et al., 2005 [35] | – | ✓ | – | – | ✓ | ✓ | ✓ | – | ✓ | – |
Ishijima et al., 2014 [36] | – | ✓ | – | – | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
Leao et al., 2018 [37] | ✓ | – | – | – | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |