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Table 1 Characteristics table

From: Systemic doxycycline as an adjunct to scaling and root planing in diabetic patients with periodontitis: a systematic review and meta-analysis

Study

Year

Gender & number (n)

Country

Number of included patients (n)

Age range/mean (years)

Periodontitis type

Probing Method

Intervention

Study duration (months)

Singh et al.

2008

Not indicated

India

Test (15)

Control (15)

Not indicated

Moderate to severe

William’s periodontal probe, sites not stated

Test = Full mouth SRP + doxycycline 100mg, 2 tablets taken on 1st day, followed by 1 tablet daily for 14 days

Control = Full mouth SRP

3

O’Connell et al.

2008

Female – 16

Male – 14

Brazil

Test (15)

Control (15)

52.9

Chronic

Computerized periodontal probe, 6 sites

Test = Full mouth SRP + doxycycline 100mg, 2 tablets taken on 1st day, followed by 1 tablet daily for 14 days

Control = Full mouth SRP

3

Al-Zahrani et al.

2009

Female – 18

Male – 11

Saudi Arabia

Test (15)

Control (14)

52.28

Moderate to severe chronic

6 sites

Test = Full mouth SRP + doxycycline 100mg, 2 tablets taken on 1st day, followed by 1 tablet daily for 14 days

Control = Full mouth SRP

3

Tsalikis et al.

2014

Female – 28

Male – 38

Greece

Test (31)

Control (35)

60.42

Chronic

Automated Florida probe, 6 sites

Test = Full mouth SRP + doxycycline 100mg, 2 tablets taken on 1st day, followed by 1 tablet daily for 20 days

Control = Full mouth SRP

3, 6

Gaikwad et al.

2013

Female – 16

Male – 34

India

Test (25)

Control (25)

30–70

Chronic generalized

UNC 15 probe, 4 sites

Test = Full mouth SRP + doxycycline 100mg 1 tablet daily for 15 days

Control = Full mouth SRP

1, 2, 3, 4

Al-Nowaiser et al.

2014

Female – 26

Male – 42

Saudi Arabia

Test (35)

Control (33)

42

Chronic

manual Florida periodontal probes, 6 sites

Test = Full mouth SRP + doxycycline 100mg 1 tablet daily for 15 days

Control = Full mouth SRP

3