Table 2 Distribution of periodontitis clinical parameters and salivary antioxidant levels among subgroups of MnSOD and Catalase genotypes
From: Associations between the phenotype and genotype of MnSOD and catalase in periodontal disease
Baseline | MnSOD genotype | p value for t-test | Catalase genotype | p valuefor t-test | ||
|---|---|---|---|---|---|---|
TT (N = 129) | TC/CC (N = 46) | CC (N = 164) | CT/TT (N = 11) | |||
Mean ± SE | Mean ± SE | |||||
PlI (%) | 58.67 ± 1.65 | 61.56 ± 2.72 | 0.36 | 60.09 ± 1.45 | 49.64 ± 5.59 | 0.07 |
BOP (%) | 43.24 ± 1.81 | 44.51 ± 3.47 | 0.72 | 43.48 ± 1.68 | 44.96 ± 5.89 | 0.82 |
PD of 4~9 mm (%) | 29.96 ± 1.28 | 32.5 ± 2.22 | 0.31 | 30.36 ± 1.13 | 34.67 ± 5.18 | 0.34 |
PD mean | 3.45 ± 0.05 | 3.47 ± 0.0.7 | 0.88 | 3.45 ± 0.04 | 3.60 ± 0.17 | 0.37 |
MnSOD (μg/ml) | 7.04 ± 1.17 | 9.05 ± 2.51 | 0.46 | 7.79 ± 1.16 | 4.29 ± 0.88 | 0.02 |
Catalase (μg/ml) | 17,347.67 ± 5322.96 | 20,703.85 ± 8324.45 | 0.74 | 19,203.72 ± 4771.04 | 3710.52 ± 2532.08 | < 0.01 |
After treatment | ||||||
 PlI (%) | 37.33 ± 1.44 | 36.12 ± 2.44 | 0.66 | 36.61 ± 1.24 | 43.04 ± 6.76 | 0.20 |
 BOP (%) | 21.7 ± 1.27 | 25.16 ± 2.95 | 0.28 | 22.07 ± 1.21 | 30.76 ± 6.86 | 0.23 |
 PD of 4~9 mm (%) | 12.99 ± 0.84 | 12.7 ± 1.47 | 0.86 | 12.81 ± 0.75 | 14.47 ± 3.3 | 0.57 |
 PD mean | 2.79 ± 0.03 | 2.80 ± 0.05 | 0.88 | 2.79 ± 0.03 | 2.87 ± 0.12 | 0.46 |
 MnSOD (μg/ml) | 4.95 ± 1.4 | 3.53 ± 0.62 | 0.35 | 4.64 ± 1.11 | 3.69 ± 1.36 | 0.59 |
 Catalase (μg/ml) | 2729.82 ± 1130.27 | 1167.21 ± 525.66 | 0.21 | 1750.44 ± 557.49 | 10,796.95 ± 10,701.48 | 0.41 |
Difference | ||||||
 Δ MnSOD (μg/ml) | 2.09 ± 0.53 | 5.52 ± 1.95 | 0.09 | 3.15 ± 0.69 | 0.6 ± 0.62 | < 0.01 |
 ΔCatalase (μg/ml) | 14,617.85 ± 5200.55 | 19,536.63 ± 8085.25 | 0.62 | 17,453.29 ± 4611.44 | − 7086.43 ± 8551.82 | 0.02 |