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Table 4 Odds ratios (ORs) of scaling and root planning treatment response in genotypes and phenotypes of antioxidants

From: Associations between the phenotype and genotype of MnSOD and catalase in periodontal disease

 

Non-response

N (%)

Response

N (%)

Crude model

OR (95% CI)

Model Ia

Model IIa

Adjusted OR (95% CI)

MnSOD genotype

 TT

20 (71.43)

109 (74.15)

1.00

1.00

 

 CT/CC

8 (28.57)

38 (25.85)

0.87 (0.35~2.14)

1.08 (0.41~2.85)

 

Catalase genotype

 CC

23 (92.86)

138 (93.88)

1.00

 

1.00

 CT/TT

2 (7.14)

9 (6.12)

0.84 (0.17~4.15)

 

0.99 (0.17~5.56)

ΔMnSOD (μg/ml)

  ≥ 0

26 (92.86)

107 (72.79)

1.00

1.00

 

  < 0

2 (7.14)

40 (27.21)

4.86 (1.10~21.42)*

5.58 (1.22~25.49)*

 

ΔCatalase (μg/ml)

  ≥ 0

26 (92.86)

106 (72.11)

1.00

 

1.00

  < 0

2 (7.14)

41 (27.89)

5.03 (1.14~22.15)*

 

5.17 (1.15~23.21)*

  1. aAdjusted for gender, years of schooling, smoking status and alcohol consumption
  2. *p<0.05
  3. MnSOD manganese superoxide dismutase, CI confidence interval