Morphological feature | Score | |||
---|---|---|---|---|
1 | 2 | 3 | 4 | |
Degree of keratinisation | Highly keratinised (> 50% of the cells) | Moderately keratinised (20–50% of the cells) | Minimal keratinisation (5–20% of the cells) | No keratinisation (0–5% of the cells) |
Nuclear polymorphism | Little nuclear polymorphism (> 75% mature cells) | Moderately abundant nuclear polymorphism (50–75% mature cells) | Abundant nuclear polymorphism (25–50% mature cells) | Extreme nuclear polymorphism (0–25% mature cells) |
Pattern of invasion | Pushing, well delineated infiltrating borders | Infiltrating, solid cords, bands and /or strands | Small groups of cords of infiltrating cells (n > 15) | Marked and widespread cellular dissociation in small groups and /or in single cells (n < 15) |
Host response (inflammatory cell infiltration) | Marked | Moderate | Slight | None |