Table 7 The distribution of the syndromic and the congenital- and multi-malformed associated anomalies of the OCs

Chromosome anomaly Syndromes (Tot. 40)

Trisomy 13 (Patau)

–

5

11

Trisomy 18 (Edwards)

2

1

1

Trisomy 21

1

–

2

Deletion 22q (DiGeorge)

–

–

1

Deletion 4p16

1

–

–

47xxy

–

1

2

46xxr

–

1

–

Other subtelomeric rearrangments

–

–

4

Syndromes without chromosome anomalies (Tot. 68)

Syndrome with arthrogryposis

–

2 + 1

1

Moebius, Beals

Meckel-Gruber

–

–

1

Van der Woude

–

2

–

Binder

1

–

–

Holoprosencephaly

1

3

10

Fraser

1–

–

–

Goldenhar

2

2

3

Kabuki

–

–

–

Treacher-Collins

3

–

Syndrome Sequence with genetic anomalies

Pierre Robin

–

35

–

Malformation/complex (Tot. 112)

MCA

16

39

53

MCA–related maternal diabetes

3

1

Totals

26

98

90