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Table 4 Quality of available evidence

From: Do probiotics promote oral health during orthodontic treatment with fixed appliances? A systematic review

Quality assessment No of patients Effect Quality
Studies Risk of bias Inconsistency Indirectness Imprecision Other Probiotic Control  
Enamel demineralization development
1 Not serious Not serious Not serious Serious1 None 42 43 No difference
Moderate
Gingival inflammation development
3 Not serious Not serious Not serious Seriousa None 81 71 No difference
Moderate
  1. aThe number of patients analyzed was limited