Table 1 Material and methods of the selected studies: country, study design, periodontal status of included cohort, follow-up, sample size, gender, smoking status, age and tested product
Study | Country | Study design | Periodontal status | Follow-up | Number, gender | Smokers | Mean (range) age | Product tested |
|---|---|---|---|---|---|---|---|---|
Bizzarro S. et al., 2017 [13] | Holland | Parallel RCT | CP | 12 months | 56(36 M, 20F) | Included | 47.8 ± 9.3 | 0,5% NaOCl solution |
Kanoriya D. et al., 2017 [14] | India | Parallel RCT | CP | 6 months | 42(NR) | Excluded | 22–55 | 0,75% boric acid gel |
Denez E.M. et al., 2016 [14] | Belgium | Split-mouth RCT | Moderate-Severe CP | 6 months | 28(NR) | Excluded | 45 ± 9.7 | 10% PVI solution |
Matesanz P. et al., 2013 [20] | Spain | Parallel RCT | PD | 6 months | 22(8 M, 14F) | Included | 50 | CHX -xanthan gel |
Krück C. et al., 2012 [21] | Germany | Parallel RCT | Moderate CP | 12 months | 51 (22 M, 29F) | NR | 51 ± 11 | 0,12 CHX solution, 7,5% PVI solution |
Sakellari D. et al., 2010 [15] | Greece | Parallel RCT | CP | 6 months | 56(25 M, 25 F) | Included | 36–75 | CHX chip |
Paolantonio M. et al., 2009 [22] | Italy | Split-mouth RCT | Moderate – advanced CP | 6 months | 98(39 M, 59F) | Excluded | 24–58 | CHX-xanthan gel |
Paolantonio M. et al., 2008 [23] | Italy | Split-mouth RCT | Moderate – advanced CP | 6 months | 82 (33 M, 49F) | Excluded | 31–63 | CHX chip |
Paolantonio M. et al., 2008 [24] | Italy | Split-mouth RCT | C Moderate – advanced CP | 6 months | 116(34 M, 82F) | Excluded | 33–65 | CHX chip |
Cosyn J. et al., 2007 [25] | Belgium | Parallel RCT | CP patients | 6 months | 33(16 M, 17 F) | NR | 50.5 ± 12.5 | CHX varnish |
Azmak N. et al., 2002 [26] | Turkey | Split-mouth RCT | Moderate-Severe CP | 6 months | 22(NR) | Excluded | 36–62 | CHX chip |
Heasman PA. et al., 2001 [27] | United Kingdom | Split-mouth RCT | Moderate-Severe CP | 6 months | 26 (8 M, 16 F) | Excluded | 42.6 ± 12.6 | CHX chip |