Table 2 MMPs SNPs in caries-free controls from this study and other caries-free controls in different populations
From: Matrix metalloproteinases gene variants and dental caries in Czech children
MMP SNP | MMP SNP localization | Minor allele | MAF | References | |||
|---|---|---|---|---|---|---|---|
N = 1006 EUR (NCBI)b | N = 52 Czech (dmft = 0) | N = 155 Czech (DMFT = 0) | Caries-free subjects (N nationality, indexa) | ||||
MMP2 (rs2287074) | exon 9 | A | 43.3% | 45.2% | 45.5% | 52.5% (20 Bulgarians, DMFT) | [19] |
MMP2 (rs243865) | promotor | T | 25.9% | 26.0% | 23.9% | 24.3% (212 Brazilians, dmft/DMFT) | [20] |
19.0% (100 Saudi Arabians, DMFT) | [21] | ||||||
MMP3 (rs679620) | exon 2 | T | 47.2% | 49.0% | 51.3% | 57.5% (20 Bulgarians, DMFT) | [19] |
MMP9 (rs17576) | exon 6 | G | 38.1% | 39.4% | 36.1% | 31.0% (211 Brazilians, dmft/DMFT) | [20] |
37.5% (100 Saudi Arabians, DMFT) | [20] | ||||||
29.2% (274 Brazilians, dmft) | [22] | ||||||
MMP13 (rs2252070) | promotor | C | 29.9% | 29.8% | 29.0% | 36.1% (208 Brazilians, dmft/DMFT) | [20] |
38.7% (97 Saudi Arabians, DMFT) | [21] | ||||||
31.9% (216 Brazilians, dmft/DMFT) | [23] | ||||||
52.6% (196 Chinese, DMFT) | [24] | ||||||
MMP16 (rs2046315) | intergenic | A | 13.8% | 20.2% | 15.5% | 13% (1769 COHRA1, dft/DMFT)b | [25] |
MMP16 (rs10429371) | intergenic | C | 21.7% | 24.0% | 20.6% | 22% (1769 COHRA1, dft/DMFT)b | [25] |
MMP20 (rs1711437) | intron | T | 42.6% | 47.1% | 44.2% | 38.3% (450 Brazilians, dmft) | [22] |
MMP20 (rs1784418) | intron 1 | T | 45.1% | 46.2% | 43.2% | 39.8% (457 Brazilians, dmft) | [22] |
51.2% (216 Brazilians, dmft/DMFT) | [23] | ||||||
43.8% (161 Brazilians, dmft/DMFT) | [26] | ||||||
40.7% (259 Turks, dmft)b | [27] | ||||||
52.9% (68 Brazilians, dmft) | [28] | ||||||
37.5% (48 Poles, dt) | [29] | ||||||