An in vitro study of the effect of 5-ALA-mediated photodynamic therapy on oral squamous cell carcinoma

BMC Oral Health

Table 3 Effect of 5-ALA combined with laser irradiation on apoptosis rate and necrosis rate of SCC25 cells in each group (\( \overline{x}\pm s \), %)

Group (5-ALA)	Early apoptosis rate	Late apoptosis rate	Necrosis rate
Blank	0.49 ± 0.07	0.33 ± 0.11	0.39 ± 0.19
100 mg/L	0.51 ± 0.13	0.44 ± 0.17	0.55 ± 0.26
Laser	0.63 ± 0.17	0.35 ± 0.08	0.48 ± 0.23
Laser + 5 mg/L	1.41 ± 0.36^*	3.09 ± 0.31^#	1.38 ± 0.34^*
Laser + 10 mg/L	1.18 ± 0.35^*	5.29 ± 0.49^#	2.73 ± 0.28^#
Laser + 25 mg/L	7.83 ± 0.98^#	17.87 ± 3.01^#	7.41 ± 1.23^#
Laser + 50 mg/L	5.47 ± 0.76^#	24.54 ± 4.02^#	13.89 ± 2.01^#
Laser + 100 mg/L	24.87 ± 4.01^#	44.28 ± 6.73^#	14.83 ± 3.03^#

The sample size at each time point was 3 in each group; compared with the blank group at the same time point, *P < 0.05; compared with the same group after 4 h, #P < 0.05

ISSN: 1472-6831