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Table 4 Protein interaction network found in the GCF with an additional seven proteins in the Search Tools or the Retrieval of Interesting Proteins/Genes (STRING) analysis. A total of six pathways were found during orthodontic treatment

From: Label-free quantitative proteomic analysis of gingival crevicular fluid to identify potential early markers for root resorption

Pathway id Pathway description Observed Gene count False discovery rate Nodes colour Associated proteins
GO:0048518 Positive regulation of biological process 16 4.31E-05 Red AGT, ANXA1, APOH, FGG, GAPDH, HBB, HRG, HSPA1A, IGHV3–11, IGJ, LDHA, MMP9, S100A8, S100A9, TMSB4X, VTN
GO:0050896 Response to stimulus 19 1.10E-05 Dark green AGT, ANXA1, APOD, APOH, AZGP1, FGG, GAPDH, HBB, HRG, HSPA1A, IGHV3–11, IGJ, LDHA, MMP9, S100A8, S100A9, TMSB4X, TYMP, VTN
GO:0008152 Metabolic process 16 0.0178 Purple AGT, AMBP, ANXA1, APOD, APOH, AZGP1, FGG, GAPDH, HBB, HSPA1A, IGHV3–11, LDHA, MMP9, S100A8, S100A9, TYMP
GO:0009987 Cellular process 20 0.0134 Dark blue AGT, AMBP, ANXA1, APOD, APOH, AZGP1, FGG, GAPDH, HBB, HRG, HSPA1A, IGHV3–11, IGJ, LDHA, MMP9, S100A8, S100A9, TMSB4X, TYMP, VTN
GO:0002376 Immune system process 12 1.42E-05 Light green ANXA1, FGG, GAPDH, HBB, HRG, HSPA1A, IGHV3–11, IGJ, MMP9, S100A8, S100A9, VTN
GO:0032879 Regulation of localization 13 4.39E-06 Yellow AGT, ANXA1, APOD, APOH, FGG, GAPDH, HRG, HSPA1A, MMP9, S100A8, S100A9, TMSB4X, VTN